PDB 2wc0
PDB Information
| PDB | 2WC0 |
| Method | X-RAY DIFFRACTION |
| Host Organism | ESCHERICHIA COLI |
| Gene Source | HOMO SAPIENS |
| Primary Citation | Molecular Basis of Catalytic Chamber-Assisted Unfolding and Cleavage of Human Insulin by Human Insulin Degrading Enzyme.
J.Biol.Chem.
|
| Header | Hydrolase/Hormone |
| Released | 2009-03-06 |
| Resolution | 2.800 |
| CATH Insert Date | 16 Aug, 2009 |
PDB Images (15)
2wc0
PDB 2wc0
2wc0A
PDB Chain 2wc0A
2wc0B
PDB Chain 2wc0B
2wc0C
PDB Chain 2wc0C
2wc0D
PDB Chain 2wc0D
2wc0E
PDB Chain 2wc0E
2wc0F
PDB Chain 2wc0F
2wc0A01
CATH Domain 2wc0A01
2wc0A02
CATH Domain 2wc0A02
2wc0A03
CATH Domain 2wc0A03
2wc0A04
CATH Domain 2wc0A04
2wc0B01
CATH Domain 2wc0B01
2wc0B02
CATH Domain 2wc0B02
2wc0B03
CATH Domain 2wc0B03
2wc0B04
CATH Domain 2wc0B04
PDB Prints
PDB Chains (6)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 16 Aug, 2009 | Chopped |
| B | 16 Aug, 2009 | Chopped |
| C | 16 Aug, 2009 | Rejected |
| D | 16 Aug, 2009 | Rejected |
| E | 16 Aug, 2009 | Rejected |
| F | 16 Aug, 2009 | Rejected |
CATH Domains (8)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 2wc0A01 | 30 Aug, 2013 | 3.30.830.10 | Assigned |
| 2wc0A02 | 30 Aug, 2013 | 3.30.830.10 | Assigned |
| 2wc0A03 | 30 Aug, 2013 | 3.30.830.10 | Assigned |
| 2wc0A04 | 30 Aug, 2013 | 3.30.830.10 | Assigned |
| 2wc0B01 | 30 Aug, 2013 | 3.30.830.10 | Assigned |
| 2wc0B02 | 30 Aug, 2013 | 3.30.830.10 | Assigned |
| 2wc0B03 | 30 Aug, 2013 | 3.30.830.10 | Assigned |
| 2wc0B04 | 30 Aug, 2013 | 3.30.830.10 | Assigned |
UniProtKB Entries (6)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P14735 | IDE_HUMAN | Homo sapiens | Insulin-degrading enzyme |
| P01308 | INS_HUMAN | Homo sapiens | Insulin |
| P01308 | INS_HUMAN | Homo sapiens | Insulin |
| P14735 | IDE_HUMAN | Homo sapiens | Insulin-degrading enzyme |
| P01308 | INS_HUMAN | Homo sapiens | Insulin |
| P01308 | INS_HUMAN | Homo sapiens | Insulin |