PDB 2wby
PDB Information
| PDB | 2WBY |
| Method | X-RAY DIFFRACTION |
| Host Organism | ESCHERICHIA COLI |
| Gene Source | HOMO SAPIENS |
| Primary Citation | Molecular Basis of Catalytic Chamber-Assisted Unfolding and Cleavage of Human Insulin by Human Insulin Degrading Enzyme.
J.Biol.Chem.
|
| Header | Hydrolase/Hormone |
| Released | 2009-03-06 |
| Resolution | 2.600 |
| CATH Insert Date | 16 Aug, 2009 |
PDB Images (15)
2wby
PDB 2wby
2wbyA
PDB Chain 2wbyA
2wbyB
PDB Chain 2wbyB
2wbyC
PDB Chain 2wbyC
2wbyD
PDB Chain 2wbyD
2wbyE
PDB Chain 2wbyE
2wbyF
PDB Chain 2wbyF
2wbyA01
CATH Domain 2wbyA01
2wbyA02
CATH Domain 2wbyA02
2wbyA03
CATH Domain 2wbyA03
2wbyA04
CATH Domain 2wbyA04
2wbyB01
CATH Domain 2wbyB01
2wbyB02
CATH Domain 2wbyB02
2wbyB03
CATH Domain 2wbyB03
2wbyB04
CATH Domain 2wbyB04
PDB Prints
PDB Chains (6)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 16 Aug, 2009 | Chopped |
| B | 16 Aug, 2009 | Chopped |
| C | 16 Aug, 2009 | Rejected |
| D | 16 Aug, 2009 | Rejected |
| E | 16 Aug, 2009 | Rejected |
| F | 16 Aug, 2009 | Rejected |
CATH Domains (8)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 2wbyA01 | 30 Aug, 2013 | 3.30.830.10 | Assigned |
| 2wbyA02 | 30 Aug, 2013 | 3.30.830.10 | Assigned |
| 2wbyA03 | 30 Aug, 2013 | 3.30.830.10 | Assigned |
| 2wbyA04 | 30 Aug, 2013 | 3.30.830.10 | Assigned |
| 2wbyB01 | 30 Aug, 2013 | 3.30.830.10 | Assigned |
| 2wbyB02 | 30 Aug, 2013 | 3.30.830.10 | Assigned |
| 2wbyB03 | 30 Aug, 2013 | 3.30.830.10 | Assigned |
| 2wbyB04 | 30 Aug, 2013 | 3.30.830.10 | Assigned |
UniProtKB Entries (6)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P14735 | IDE_HUMAN | Homo sapiens | Insulin-degrading enzyme |
| P14735 | IDE_HUMAN | Homo sapiens | Insulin-degrading enzyme |
| P01308 | INS_HUMAN | Homo sapiens | Insulin |
| P01308 | INS_HUMAN | Homo sapiens | Insulin |
| P01308 | INS_HUMAN | Homo sapiens | Insulin |
| P01308 | INS_HUMAN | Homo sapiens | Insulin |