PDB 2uzd

PDB Information

PDB2UZD
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Discovery of a Potent Cdk2 Inhibitor with a Novel Binding Mode, Using Virtual Screening and Initial, Structure-Guided Lead Scoping.
Richardson, C.M., Nunns, C.L., Williamson, D.S., Parratt, M.J., Dokurno, P., Howes, R., Borgognoni, J., Drysdale, M.J., Finch, H., Hubbard, R.E., Jackson, P.S., Kierstan, P., Lentzen, G., Moore, J.D., Murray, J.B., Simmonite, H., Surgenor, A.E., Torrance, C.J.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2007-04-27
Resolution2.720
CATH Insert Date28 Jun, 2007

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 28 Jun, 2007 Chopped
B 28 Jun, 2007 Chopped
C 28 Jun, 2007 Chopped
D 28 Jun, 2007 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
2uzdA01 22 Jul, 2007 3.30.200.20 Assigned
2uzdA02 22 Jul, 2007 1.10.510.10 Assigned
2uzdB01 15 Jul, 2007 1.10.472.10 Assigned
2uzdB02 15 Jul, 2007 1.10.472.10 Assigned
2uzdC01 22 Jul, 2007 3.30.200.20 Assigned
2uzdC02 22 Jul, 2007 1.10.510.10 Assigned
2uzdD01 15 Jul, 2007 1.10.472.10 Assigned
2uzdD02 15 Jul, 2007 1.10.472.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2