PDB 2uzb

PDB Information

PDB2UZB
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Discovery of a Potent Cdk2 Inhibitor with a Novel Binding Mode, Using Virtual Screening and Initial, Structure-Guided Lead Scoping.
Richardson, C.M., Nunns, C.L., Williamson, D.S., Parratt, M.J., Dokurno, P., Howes, R., Borgognoni, J., Drysdale, M.J., Finch, H., Hubbard, R.E., Jackson, P.S., Kierstan, P., Lentzen, G., Moore, J.D., Murray, J.B., Simmonite, H., Surgenor, A.E., Torrance, C.J.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2007-04-27
Resolution2.700
CATH Insert Date28 Jun, 2007

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 28 Jun, 2007 Chopped
B 28 Jun, 2007 Chopped
C 28 Jun, 2007 Chopped
D 28 Jun, 2007 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
2uzbA01 22 Jul, 2007 3.30.200.20 Assigned
2uzbA02 22 Jul, 2007 1.10.510.10 Assigned
2uzbB01 15 Jul, 2007 1.10.472.10 Assigned
2uzbB02 15 Jul, 2007 1.10.472.10 Assigned
2uzbC01 22 Jul, 2007 3.30.200.20 Assigned
2uzbC02 22 Jul, 2007 1.10.510.10 Assigned
2uzbD01 15 Jul, 2007 1.10.472.10 Assigned
2uzbD02 15 Jul, 2007 1.10.472.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2