PDB 2uwd

PDB Information

PDB2UWD
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Inhibition of the heat shock protein 90 molecular chaperone in vitro and in vivo by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analogues.
Sharp, S.Y., Prodromou, C., Boxall, K., Powers, M.V., Holmes, J.L., Box, G., Matthews, T.P., Cheung, K.M., Kalusa, A., James, K., Hayes, A., Hardcastle, A., Dymock, B., Brough, P.A., Barril, X., Cansfield, J.E., Wright, L., Surgenor, A., Foloppe, N., Hubbard, R.E., Aherne, W., Pearl, L., Jones, K., McDonald, E., Raynaud, F., Eccles, S., Drysdale, M., Workman, P.
Mol. Cancer Ther.
HeaderChaperone
Released2007-03-20
Resolution1.900
CATH Insert Date26 Apr, 2007

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 26 Apr, 2007 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
2uwdA00 16 Jul, 2007 3.30.565.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P07900 HS90A_HUMAN Homo sapiens Heat shock protein HSP 90-alpha