PDB Information

PDB2RBE
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
The discovery of 2-anilinothiazolones as 11beta-HSD1 inhibitors.
Yuan, C., St Jean, D.J., Liu, Q., Cai, L., Li, A., Han, N., Moniz, G., Askew, B., Hungate, R.W., Johansson, L., Tedenborg, L., Pyring, D., Williams, M., Hale, C., Chen, M., Cupples, R., Zhang, J., Jordan, S., Bartberger, M.D., Sun, Y., Emery, M., Wang, M., Fotsch, C.
Bioorg.Med.Chem.Lett.
HeaderOxidoreductase
Released2007-09-18
Resolution1.900
CATH Insert Date17 Jan, 2008

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 17 Jan, 2008 Chopped
B 17 Jan, 2008 Chopped
C 17 Jan, 2008 Chopped
D 17 Jan, 2008 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
2rbeA00 05 Dec, 2008 3.40.50.720 Assigned
2rbeB00 05 Dec, 2008 3.40.50.720 Assigned
2rbeC00 05 Dec, 2008 3.40.50.720 Assigned
2rbeD00 05 Dec, 2008 3.40.50.720 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P28845 DHI1_HUMAN Homo sapiens Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845 DHI1_HUMAN Homo sapiens Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845 DHI1_HUMAN Homo sapiens Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845 DHI1_HUMAN Homo sapiens Corticosteroid 11-beta-dehydrogenase isozyme 1