PDB 2qzk

PDB Information

PDB2QZK
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Strategies toward improving the brain penetration of macrocyclic tertiary carbinamine BACE-1 inhibitors.
Moore, K.P., Zhu, H., Rajapakse, H.A., McGaughey, G.B., Colussi, D., Price, E.A., Sankaranarayanan, S., Simon, A.J., Pudvah, N.T., Hochman, J.H., Allison, T., Munshi, S.K., Graham, S.L., Vacca, J.P., Nantermet, P.G.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2007-08-16
Resolution1.800
CATH Insert Date01 May, 2008

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 01 May, 2008 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2qzkA01 02 May, 2008 2.40.70.10 Assigned
2qzkA02 02 May, 2008 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1