PDB 2pr3

PDB Information

PDB2PR3
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-based drug design of pyrrolidine-1, 2-dicarboxamides as a novel series of orally bioavailable factor Xa inhibitors
Van Huis, C.A., Bigge, C.F., Casimiro-Garcia, A., Cody, W.L., Dudley, D.A., Filipski, K.J., Heemstra, R.J., Kohrt, J.T., Narasimhan, L.S., Schaum, R.P., Zhang, E., Bryant, J.W., Haarer, S., Janiczek, N., Leadley, R.J., McClanahan, T., Thomas Peterson, J., Welch, K.M., Edmunds, J.J.
Chem.Biol.Drug Des.
HeaderBlood Clotting
Released2007-05-03
Resolution1.500
CATH Insert Date07 Nov, 2007

PDB Images (6)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 Nov, 2007 Chopped
B 08 Nov, 2007 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
2pr3A01 23 Nov, 2007 2.40.10.10 Assigned
2pr3A02 23 Nov, 2007 2.40.10.10 Assigned
2pr3B00 23 Nov, 2007 2.10.25.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00742 FA10_HUMAN Homo sapiens Coagulation factor X
P00742 FA10_HUMAN Homo sapiens Coagulation factor X