PDB Information

PDB2PK5
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHuman immunodeficiency virus 1
Primary Citation
Compensating enthalpic and entropic changes hinder binding affinity optimization.
Lafont, V., Armstrong, A.A., Ohtaka, H., Kiso, Y., Mario Amzel, L., Freire, E.
Chem.Biol.Drug Des.
HeaderHydrolase/Hydrolase Inhibitor
Released2007-04-17
Resolution1.900
CATH Insert Date10 May, 2007

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 10 May, 2007 Chopped
B 10 May, 2007 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2pk5A00 19 Jul, 2007 2.40.70.10 Assigned
2pk5B00 19 Jul, 2007 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9J2P7 Q9J2P7_9HIV1 Human immunodeficiency virus 1 Protease
Q9J2P7 Q9J2P7_9HIV1 Human immunodeficiency virus 1 Protease