PDB 2ph8

PDB Information

PDB2PH8
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Strategies toward improving the brain penetration of macrocyclic tertiary carbinamine BACE-1 inhibitors.
Moore, K.P., Zhu, H., Rajapakse, H.A., McGaughey, G.B., Colussi, D., Price, E.A., Sankaranarayanan, S., Simon, A.J., Pudvah, N.T., Hochman, J.H., Allison, T., Munshi, S.K., Graham, S.L., Vacca, J.P., Nantermet, P.G.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2007-04-10
Resolution1.700
CATH Insert Date24 Apr, 2008

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 24 Apr, 2008 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2ph8A01 25 Apr, 2008 2.40.70.10 Assigned
2ph8A02 25 Apr, 2008 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1