PDB Information

PDB2OOH
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor.
Crichlow, G.V., Cheng, K.F., Dabideen, D., Ochani, M., Aljabari, B., Pavlov, V.A., Miller, E.J., Lolis, E., Al-Abed, Y.
J.Biol.Chem.
HeaderIsomerase
Released2007-01-25
Resolution1.850
CATH Insert Date07 Jun, 2007

PDB Images (7)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 07 Jun, 2007 Chopped
B 07 Jun, 2007 Chopped
C 07 Jun, 2007 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
2oohA00 14 Jul, 2007 3.30.429.10 Assigned
2oohB00 14 Jul, 2007 3.30.429.10 Assigned
2oohC00 13 Jul, 2007 3.30.429.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P14174 MIF_HUMAN Homo sapiens Macrophage migration inhibitory factor
P14174 MIF_HUMAN Homo sapiens Macrophage migration inhibitory factor
P14174 MIF_HUMAN Homo sapiens Macrophage migration inhibitory factor