PDB 2lwi

PDB Information

PDB2LWI
MethodSOLUTION NMR
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
In silico discovery of small-molecule Ras inhibitors that display antitumor activity by blocking the Ras-effector interaction.
Shima, F., Yoshikawa, Y., Ye, M., Araki, M., Matsumoto, S., Liao, J., Hu, L., Sugimoto, T., Ijiri, Y., Takeda, A., Nishiyama, Y., Sato, C., Muraoka, S., Tamura, A., Osoda, T., Tsuda, K.I., Miyakawa, T., Fukunishi, H., Shimada, J., Kumasaka, T., Yamamoto, M., Kataoka, T.
Proc.Natl.Acad.Sci.USA
HeaderSignaling Protein/Inhibitor
Released2012-08-01
Resolution
CATH Insert Date07 Jul, 2013

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
2lwiA00 09 Aug, 2013 3.40.50.300 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P01112 RASH_HUMAN Homo sapiens GTPase HRas
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