PDB Information

PDB2ILM
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Evidence that two enzyme-derived histidine ligands are sufficient for iron binding and catalysis by factor inhibiting HIF (FIH).
Hewitson, K.S., Holmes, S.L., Ehrismann, D., Hardy, A.P., Chowdhury, R., Schofield, C.J., McDonough, M.A.
J.Biol.Chem.
HeaderTranscription Regulator, Oxidoreductase
Released2006-10-03
Resolution2.300
CATH Insert Date07 Nov, 2007

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 Nov, 2007 Chopped
S 08 Nov, 2007 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2ilmA01 23 Nov, 2007 2.60.120.10 Assigned
2ilmA02 23 Nov, 2007 1.10.287.1010 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9NWT6 HIF1N_HUMAN Homo sapiens Hypoxia-inducible factor 1-alpha inhibitor
Q16665 HIF1A_HUMAN Homo sapiens Hypoxia-inducible factor 1-alpha