PDB 2gk1
PDB Information
| PDB | 2GK1 |
| Method | X-RAY DIFFRACTION |
| Host Organism | |
| Gene Source | |
| Primary Citation | Crystallographic Structure of Human beta-Hexosaminidase A: Interpretation of Tay-Sachs Mutations and Loss of G(M2) Ganglioside Hydrolysis.
J.Mol.Biol.
|
| Header | Hydrolase |
| Released | 2006-03-31 |
| Resolution | 3.250 |
| CATH Insert Date | 14 Jul, 2006 |
PDB Images (33)
2gk1
PDB 2gk1
2gk1A
PDB Chain 2gk1A
2gk1B
PDB Chain 2gk1B
2gk1C
PDB Chain 2gk1C
2gk1D
PDB Chain 2gk1D
2gk1E
PDB Chain 2gk1E
2gk1F
PDB Chain 2gk1F
2gk1G
PDB Chain 2gk1G
2gk1H
PDB Chain 2gk1H
2gk1I
PDB Chain 2gk1I
2gk1J
PDB Chain 2gk1J
2gk1K
PDB Chain 2gk1K
2gk1L
PDB Chain 2gk1L
2gk1M
PDB Chain 2gk1M
2gk1N
PDB Chain 2gk1N
2gk1O
PDB Chain 2gk1O
2gk1P
PDB Chain 2gk1P
2gk1Q
PDB Chain 2gk1Q
2gk1R
PDB Chain 2gk1R
2gk1S
PDB Chain 2gk1S
2gk1T
PDB Chain 2gk1T
2gk1I01
CATH Domain 2gk1I01
2gk1I02
CATH Domain 2gk1I02
2gk1J01
CATH Domain 2gk1J01
2gk1J02
CATH Domain 2gk1J02
2gk1K01
CATH Domain 2gk1K01
2gk1K02
CATH Domain 2gk1K02
2gk1L01
CATH Domain 2gk1L01
2gk1L02
CATH Domain 2gk1L02
2gk1N00
CATH Domain 2gk1N00
2gk1P00
CATH Domain 2gk1P00
2gk1R00
CATH Domain 2gk1R00
2gk1T00
CATH Domain 2gk1T00
PDB Prints
PDB Chains (20)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 14 Jul, 2006 | Holding pen |
| B | 14 Jul, 2006 | Holding pen |
| C | 14 Jul, 2006 | Holding pen |
| D | 14 Jul, 2006 | Holding pen |
| E | 14 Jul, 2006 | Holding pen |
| F | 14 Jul, 2006 | Holding pen |
| G | 14 Jul, 2006 | Holding pen |
| H | 14 Jul, 2006 | Holding pen |
| I | 14 Nov, 2017 | Chopped |
| J | 14 Nov, 2017 | Chopped |
| K | 14 Nov, 2017 | Chopped |
| L | 14 Nov, 2017 | Chopped |
| M | 14 Nov, 2017 | Holding pen |
| N | 14 Nov, 2017 | Chopped |
| O | 14 Nov, 2017 | Holding pen |
| P | 14 Nov, 2017 | Chopped |
| Q | 14 Nov, 2017 | Holding pen |
| R | 14 Nov, 2017 | Chopped |
| S | 14 Nov, 2017 | Holding pen |
| T | 14 Nov, 2017 | Chopped |
CATH Domains (12)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 2gk1I01 | 16 Dec, 2017 | Cathedral cath submit | |
| 2gk1I02 | 16 Dec, 2017 | 3.20.20.80 | Assigned |
| 2gk1J01 | 16 Dec, 2017 | Holding pen | |
| 2gk1J02 | 16 Dec, 2017 | 3.20.20.80 | Assigned |
| 2gk1K01 | 16 Dec, 2017 | Holding pen | |
| 2gk1K02 | 16 Dec, 2017 | 3.20.20.80 | Assigned |
| 2gk1L01 | 16 Dec, 2017 | Holding pen | |
| 2gk1L02 | 16 Dec, 2017 | 3.20.20.80 | Assigned |
| 2gk1N00 | 16 Dec, 2017 | Holding pen | |
| 2gk1P00 | 16 Dec, 2017 | Holding pen | |
| 2gk1R00 | 16 Dec, 2017 | Holding pen | |
| 2gk1T00 | 16 Dec, 2017 | Holding pen |
UniProtKB Entries (20)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P06865 | HEXA_HUMAN | Homo sapiens | Beta-hexosaminidase subunit alpha |
| P07686 | HEXB_HUMAN | Homo sapiens | Beta-hexosaminidase subunit beta |
| P07686 | HEXB_HUMAN | Homo sapiens | Beta-hexosaminidase subunit beta |
| P07686 | HEXB_HUMAN | Homo sapiens | Beta-hexosaminidase subunit beta |
| P07686 | HEXB_HUMAN | Homo sapiens | Beta-hexosaminidase subunit beta |
| P07686 | HEXB_HUMAN | Homo sapiens | Beta-hexosaminidase subunit beta |
| P06865 | HEXA_HUMAN | Homo sapiens | Beta-hexosaminidase subunit alpha |
| P07686 | HEXB_HUMAN | Homo sapiens | Beta-hexosaminidase subunit beta |
| P07686 | HEXB_HUMAN | Homo sapiens | Beta-hexosaminidase subunit beta |
| P06865 | HEXA_HUMAN | Homo sapiens | Beta-hexosaminidase subunit alpha |
| P06865 | HEXA_HUMAN | Homo sapiens | Beta-hexosaminidase subunit alpha |
| P06865 | HEXA_HUMAN | Homo sapiens | Beta-hexosaminidase subunit alpha |
| P07686 | HEXB_HUMAN | Homo sapiens | Beta-hexosaminidase subunit beta |
| P07686 | HEXB_HUMAN | Homo sapiens | Beta-hexosaminidase subunit beta |
| P06865 | HEXA_HUMAN | Homo sapiens | Beta-hexosaminidase subunit alpha |
| P06865 | HEXA_HUMAN | Homo sapiens | Beta-hexosaminidase subunit alpha |
| P06865 | HEXA_HUMAN | Homo sapiens | Beta-hexosaminidase subunit alpha |
| P07686 | HEXB_HUMAN | Homo sapiens | Beta-hexosaminidase subunit beta |
| P07686 | HEXB_HUMAN | Homo sapiens | Beta-hexosaminidase subunit beta |
| P07686 | HEXB_HUMAN | Homo sapiens | Beta-hexosaminidase subunit beta |