PDB Information

PDB2GH5
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
A fluoro analogue of the menadione derivative 6-[2'-(3'-methyl)-1',4'-naphthoquinolyl]hexanoic acid is a suicide substrate of glutathione reductase. Crystal structure of the alkylated human enzyme
Bauer, H., Fritz-Wolf, K., Winzer, A., Little, S., Yardley, V., Vezin, H., Palfey, B., Schirmer, R.H., Davioud-Charvet, E.
J.Am.Chem.Soc.
HeaderOxidoreductase
Released2006-03-25
Resolution1.700
CATH Insert Date28 Sep, 2006

PDB Images (9)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 28 Sep, 2006 Chopped
B 28 Sep, 2006 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
2gh5A01 15 Oct, 2006 3.50.50.60 Assigned
2gh5A02 15 Oct, 2006 3.50.50.60 Assigned
2gh5A03 15 Oct, 2006 3.30.390.30 Assigned
2gh5B01 01 Nov, 2006 3.50.50.60 Assigned
2gh5B02 01 Nov, 2006 3.50.50.60 Assigned
2gh5B03 01 Nov, 2006 3.30.390.30 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00390 GSHR_HUMAN Homo sapiens Glutathione reductase, mitochondrial
P00390 GSHR_HUMAN Homo sapiens Glutathione reductase, mitochondrial