PDB 2flb

PDB Information

PDB2FLB
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of novel hydroxy pyrazole based factor IXa inhibitor.
Vijaykumar, D., Sprengeler, P.A., Shaghafi, M., Spencer, J.R., Katz, B.A., Yu, C., Rai, R., Young, W.B., Schultz, B., Janc, J.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Blood Clotting
Released2006-01-05
Resolution1.950
CATH Insert Date14 Jul, 2006

PDB Images (9)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
H 14 Jul, 2006 Chopped
L 14 Jul, 2006 Chopped
T 14 Jul, 2006 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
2flbH01 22 Oct, 2006 2.40.10.10 Assigned
2flbH02 22 Oct, 2006 2.40.10.10 Assigned
2flbL01 28 Nov, 2006 2.10.25.10 Assigned
2flbL02 28 Nov, 2006 2.10.25.10 Assigned
2flbT00 16 Oct, 2006 2.60.40.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P13726 TF_HUMAN Homo sapiens Tissue factor
P08709 FA7_HUMAN Homo sapiens Coagulation factor VII
P08709 FA7_HUMAN Homo sapiens Coagulation factor VII