PDB Information

PDB2F8G
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHuman immunodeficiency virus 1
Primary Citation
Effectiveness of Nonpeptide Clinical Inhibitor TMC-114 on HIV-1 Protease with Highly Drug Resistant Mutations D30N, I50V, and L90M.
Kovalevsky, A.Y., Tie, Y., Liu, F., Boross, P.I., Wang, Y.F., Leshchenko, S., Ghosh, A.K., Harrison, R.W., Weber, I.T.
J.Med.Chem.
HeaderHydrolase
Released2005-12-02
Resolution1.220
CATH Insert Date15 Mar, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 15 Mar, 2006 Chopped
B 15 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2f8gA00 17 Mar, 2006 2.40.70.10 Assigned
2f8gB00 17 Mar, 2006 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P04587 POL_HV1B5 Human immunodeficiency virus type 1 (BH5 ISOLATE) Gag-Pol polyprotein
P04587 POL_HV1B5 Human immunodeficiency virus type 1 (BH5 ISOLATE) Gag-Pol polyprotein