PDB 2f53

PDB Information

PDB2F53
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21
Gene SourceHomo sapiens
Primary Citation
Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity.
Dunn, S.M., Rizkallah, P.J., Baston, E., Mahon, T., Cameron, B., Moysey, R., Gao, F., Sami, M., Boulter, J., Li, Y., Jakobsen, B.K.
Protein Sci.
HeaderImmune System
Released2005-11-25
Resolution2.100
CATH Insert Date14 Jul, 2006

PDB Images (13)

PDB Prints

PDB Chains (5)

Chain ID Date inserted into CATH CATH Status
A 14 Jul, 2006 Chopped
B 14 Jul, 2006 Chopped
C 14 Jul, 2006 Rejected
D 14 Jul, 2006 Chopped
E 14 Jul, 2006 Chopped

CATH Domains (7)

Domain ID Date inserted into CATH Superfamily CATH Status
2f53A01 29 Nov, 2006 3.30.500.10 Assigned
2f53A02 29 Nov, 2006 2.60.40.10 Assigned
2f53B00 16 Oct, 2006 2.60.40.10 Assigned
2f53D01 15 Jul, 2007 2.60.40.10 Assigned
2f53D02 15 Jul, 2007 2.60.40.10 Assigned
2f53E01 14 Jul, 2007 2.60.40.10 Assigned
2f53E02 14 Jul, 2007 2.60.40.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P78358 CTG1B_HUMAN Homo sapiens Cancer/testis antigen 1
P61769 B2MG_HUMAN Homo sapiens Beta-2-microglobulin
P01848 TRAC_HUMAN Homo sapiens T cell receptor alpha constant
P01892 1A02_HUMAN Homo sapiens HLA class I histocompatibility antigen, A-2 alpha chain