PDB Information

PDB2BRE
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceSACCHAROMYCES CEREVISIAE
Primary Citation
The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors.
Cheung, K.M., Matthews, T.P., James, K., Rowlands, M.G., Boxall, K.J., Sharp, S.Y., Maloney, A., Roe, S.M., Prodromou, C., Pearl, L.H., Aherne, G.W., McDonald, E., Workman, P.
Bioorg. Med. Chem. Lett.
HeaderChaperone
Released2005-05-04
Resolution2.000
CATH Insert Date05 Mar, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2breA00 10 Mar, 2006 3.30.565.10 Assigned
2breB00 10 Mar, 2006 3.30.565.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P02829 HSP82_YEAST Saccharomyces cerevisiae S288C ATP-dependent molecular chaperone HSP82
P02829 HSP82_YEAST Saccharomyces cerevisiae S288C ATP-dependent molecular chaperone HSP82