PDB 2bm2

PDB Information

PDB2BM2
MethodX-RAY DIFFRACTION
Host OrganismPICHIA PASTORIS
Gene SourceHOMO SAPIENS
Primary Citation
Structure Based Design of 4-(3-Aminomethylphenyl) Piperidinyl-1-Amides: Novel, Potent, Selective, and Orally Bioavailable Inhibitors of Bii Tryptase
Levell, J., Astles, P., Eastwood, P., Cairns, J., Houille, O., Aldous, S., Merriman, G., Whitley, B., Pribish, J., Czekaj, M., Liang, G., Maignan, S., Guilloteau, J.-P., Dupuy, A., Davidson, J., Harrison, T., Morley, A., Watson, S., Fenton, G., Mccarthy, C., Romano, J., Mathew, R., Engers, D., Gardyan, M., Sides, K., Kwong, J., Tsay, J., Rebello, S., Shen, L., Wang, J., Luo, Y., Giardino, O., Lim, H.-K., Smith, K., Pauls, H.
Bioorg.Med.Chem.
HeaderHydrolase
Released2005-03-08
Resolution2.200
CATH Insert Date05 Mar, 2006

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Chopped
D 05 Mar, 2006 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
2bm2A01 10 Mar, 2006 2.40.10.10 Assigned
2bm2A02 10 Mar, 2006 2.40.10.10 Assigned
2bm2B01 10 Mar, 2006 2.40.10.10 Assigned
2bm2B02 10 Mar, 2006 2.40.10.10 Assigned
2bm2C01 10 Mar, 2006 2.40.10.10 Assigned
2bm2C02 10 Mar, 2006 2.40.10.10 Assigned
2bm2D01 10 Mar, 2006 2.40.10.10 Assigned
2bm2D02 10 Mar, 2006 2.40.10.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P20231 TRYB2_HUMAN Homo sapiens Tryptase beta-2
P20231 TRYB2_HUMAN Homo sapiens Tryptase beta-2
P20231 TRYB2_HUMAN Homo sapiens Tryptase beta-2
P20231 TRYB2_HUMAN Homo sapiens Tryptase beta-2
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