PDB Information

PDB1ZGI
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Development of an oxazolopyridine series of dual thrombin/factor Xa inhibitors via structure-guided lead optimization.
Deng, J.Z., McMasters, D.R., Rabbat, P.M., Williams, P.D., Coburn, C.A., Yan, Y., Kuo, L.C., Lewis, S.D., Lucas, B.J., Krueger, J.A., Strulovici, B., Vacca, J.P., Lyle, T.A., Burgey, C.S.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2005-04-21
Resolution2.200
CATH Insert Date05 Mar, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1zgiA01 14 Jul, 2007 2.40.10.10 Assigned
1zgiA02 14 Jul, 2007 2.40.10.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P28511 HIR3C_HIRME Hirudo medicinalis Hirudin-3B'
P00734 THRB_HUMAN Homo sapiens Prothrombin