PDB 1z6e

PDB Information

PDB1Z6E
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Discovery of 1-(3'-aminobenzisoxazol-5'-yl)-3-trifluoromethyl-N-[2-fluoro-4-[(2'-dimethylaminomethyl)imidazol-1-yl]phenyl]-1H-pyrazole-5-carboxyamide hydrochloride (razaxaban), a highly potent, selective, and orally bioavailable factor Xa inhibitor.
Quan, M.L., Lam, P.Y.S., Han, Q., Pinto, D.J.P., He, M.Y., Li, R., Ellis, C.D., Clark, C.G., Teleha, C.A., Sun, J.-H., Alexander, R.S., Bai, S., Luettgen, J.M., Knabb, R.M., Wong, P.C., Wexler, R.R.
J.Med.Chem.
HeaderHydrolase
Released2005-03-22
Resolution1.800
CATH Insert Date14 Jul, 2006

PDB Images (6)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 14 Jul, 2006 Chopped
L 04 Oct, 2010 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
1z6eA01 16 Oct, 2006 2.40.10.10 Assigned
1z6eA02 16 Oct, 2006 2.40.10.10 Assigned
1z6eL00 08 Oct, 2010 2.10.25.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00742 FA10_HUMAN Homo sapiens Coagulation factor X
P00742 FA10_HUMAN Homo sapiens Coagulation factor X