PDB 1xkk

PDB Information

PDB1XKK
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
A unique structure for epidermal growth factor receptor bound to GW572016 (Lapatinib): relationships among protein conformation, inhibitor off-rate, and receptor activity in tumor cells.
Wood, E.R., Truesdale, A.T., McDonald, O.B., Yuan, D., Hassell, A., Dickerson, S.H., Ellis, B., Pennisi, C., Horne, E., Lackey, K., Alligood, K.J., Rusnak, D.W., Gilmer, T.M., Shewchuk, L.
Cancer Res.
HeaderTransferase
Released2004-09-29
Resolution2.400
CATH Insert Date05 Mar, 2006

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1xkkA01 24 Nov, 2006 3.30.200.20 Assigned
1xkkA02 24 Nov, 2006 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor