PDB 1x70

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Overview

PDB Information

PDB	1X70
Method	X-RAY DIFFRACTION
Host Organism	Trichoplusia ni
Gene Source	Homo sapiens
Primary Citation	(2R)-4-Oxo-4-[3-(Trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin- 7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine: A Potent, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes Kim, D., Wang, L., Beconi, M., Eiermann, G.J., Fisher, M.H., He, H., Hickey, G.J., Kowalchick, J.E., Leiting, B., Lyons, K., Marsilio, F., McCann, M.E., Patel, R.A., Petrov, A., Scapin, G., Patel, S.B., Roy, R.S., Wu, J.K., Wyvratt, M.J., Zhang, B.B., Zhu, L., Thornberry, N.A., Weber, A.E. J.Med.Chem.
Header	Hydrolase
Released	2004-08-12
Resolution	2.100
CATH Insert Date	05 Mar, 2006

PDB Images (7)

Image of CATH 1x70

1x70

PDB 1x70

Image of CATH 1x70A

1x70A

PDB Chain 1x70A

Image of CATH 1x70B

1x70B

PDB Chain 1x70B

Image of CATH 1x70A01

1x70A01

CATH Domain 1x70A01

Image of CATH 1x70A02

1x70A02

CATH Domain 1x70A02

Image of CATH 1x70B01

1x70B01

CATH Domain 1x70B01

Image of CATH 1x70B02

1x70B02

CATH Domain 1x70B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	05 Mar, 2006	Chopped
B	05 Mar, 2006	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
1x70A01	09 Mar, 2006	3.40.50.1820	Assigned
1x70A02	09 Mar, 2006	2.140.10.30	Assigned
1x70B01	09 Mar, 2006	3.40.50.1820	Assigned
1x70B02	09 Mar, 2006	2.140.10.30	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P27487	DPP4_HUMAN	Homo sapiens	Dipeptidyl peptidase 4
P27487	DPP4_HUMAN	Homo sapiens	Dipeptidyl peptidase 4