PDB 1tom

PDB Information

PDB1TOM
MethodX-RAY DIFFRACTION
Host Organism
Gene SourceHirudo medicinalis
Primary Citation
Synthesis, evaluation, and crystallographic analysis of L-371,912: A potent and selective active-site thrombin inhibitor.
Lyle, T.A., Chen, Z.G., Appleby, S.D., Freidinger, R.M., Gardell, S.J., Lewis, S.D., Li, Y., Lyle, E.A., Lynch, J.J., Mulichak, A.M., Ng, A.S., NaylorOlsen, A.M., Sanders, W.M.
Bioorg.Med.Chem.Lett.
HeaderBlood Coagulation/Hydrolase Inhibitor
Released1996-12-06
Resolution1.800
CATH Insert Date05 Mar, 2006

PDB Images (6)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
H 05 Mar, 2006 Chopped
I 05 Mar, 2006 Rejected
L 05 Mar, 2006 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1tomH01 18 Jan, 2007 2.40.10.10 Assigned
1tomH02 18 Jan, 2007 2.40.10.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P00734 THRB_HUMAN Homo sapiens Prothrombin
P00734 THRB_HUMAN Homo sapiens Prothrombin
P28507 HIR3A_HIRME Hirudo medicinalis Hirudin-3A