PDB 1tft

PDB Information

PDB1TFT
MethodSOLUTION NMR
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of potent antagonists of the antiapoptotic protein XIAP for the treatment of cancer.
Oost, T.K., Sun, C., Armstrong, R.C., Al-Assaad, A.S., Betz, S.F., Deckwerth, T.L., Ding, H., Elmore, S.W., Meadows, R.P., Olejniczak, E.T., Oleksijew, A.K., Oltersdorf, T., Rosenberg, S.H., Shoemaker, A.R., Tomaselli, K.J., Zou, H., Fesik, S.W.
J.Med.Chem.
HeaderApoptosis
Released2004-05-27
Resolution
CATH Insert Date05 Mar, 2006

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
1tftA00 09 Mar, 2006 1.10.1170.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P98170 XIAP_HUMAN Homo sapiens E3 ubiquitin-protein ligase XIAP