PDB Information

PDB1T4V
MethodX-RAY DIFFRACTION
Host Organism
Gene SourceHomo sapiens
Primary Citation
Oxyguanidines. Part 2: Discovery of a novel orally active thrombin inhibitor through structure-based drug design and parallel synthesis
Lu, T., Markotan, T., Coppo, F., Tomczuk, B., Crysler, C., Eisennagel, S., Spurlino, J., Gremminger, L., Soll, R.M., Giardino, E.C., Bone, R.
BIOORG.MED.CHEM.LETT.
HeaderHydrolase/Hydrolase Inhibitor
Released2004-04-30
Resolution2.000
CATH Insert Date05 Mar, 2006

PDB Images (6)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
H 05 Mar, 2006 Chopped
I 05 Mar, 2006 Rejected
L 05 Mar, 2006 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1t4vH01 16 Oct, 2006 2.40.10.10 Assigned
1t4vH02 16 Oct, 2006 2.40.10.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P28507 HIR3A_HIRME Hirudo medicinalis Hirudin-3A
P00734 THRB_HUMAN Homo sapiens Prothrombin
P00734 THRB_HUMAN Homo sapiens Prothrombin