PDB 1t4f

PDB Information

PDB1T4F
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21
Gene SourceHomo sapiens
Primary Citation
Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells
Grasberger, B.L., Lu, T., Schubert, C., Parks, D.J., Carver, T.E., Koblish, H.K., Cummings, M.D., LaFrance, L.V., Milkiewicz, K.L.
J.Med.Chem.
HeaderLigase
Released2004-04-29
Resolution1.900
CATH Insert Date05 Mar, 2006

PDB Images (4)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
M 05 Mar, 2006 Chopped
P 05 Mar, 2006 Rejected

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
1t4fM00 09 Mar, 2006 1.10.245.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2