PDB 1t4e

PDB Links
Overview

PDB Information

PDB	1T4E
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli BL21
Gene Source	Homo sapiens
Primary Citation	Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells Grasberger, B.L., Lu, T., Schubert, C., Parks, D.J., Carver, T.E., Koblish, H.K., Cummings, M.D., LaFrance, L.V. J.Med.Chem.
Header	Ligase
Released	2004-04-29
Resolution	2.600
CATH Insert Date	05 Mar, 2006

PDB Images (5)

Image of CATH 1t4e

1t4e

PDB 1t4e

Image of CATH 1t4eA

1t4eA

PDB Chain 1t4eA

Image of CATH 1t4eB

1t4eB

PDB Chain 1t4eB

Image of CATH 1t4eA00

1t4eA00

CATH Domain 1t4eA00

Image of CATH 1t4eB00

1t4eB00

CATH Domain 1t4eB00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	05 Mar, 2006	Chopped
B	05 Mar, 2006	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
1t4eA00	19 Oct, 2006	1.10.245.10	Assigned
1t4eB00	19 Oct, 2006	1.10.245.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q00987	MDM2_HUMAN	Homo sapiens	E3 ubiquitin-protein ligase Mdm2
Q00987	MDM2_HUMAN	Homo sapiens	E3 ubiquitin-protein ligase Mdm2