PDB 1sv5

PDB Information

PDB1SV5
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus 1
Primary Citation
Roles of Conformational and Positional Adaptability in Structure-Based Design of TMC125-R165335 (Etravirine) and Related Non-nucleoside Reverse Transcriptase Inhibitors That Are Highly Potent and Effective against Wild-Type and Drug-Resistant HIV-1 Variants
Das, K., Clark Jr., A.D., Lewi, P.J., Heeres, J., De Jonge, M.R., Koymans, L.M., Vinkers, H.M., Daeyaert, F., Ludovici, D.W., Kukla, M.J., De Corte, B., Kavash, R.W., Ho, C.Y., Ye, H., Lichtenstein, M.A., Andries, K., Pauwles, R., Debethune, M.-P., Boyer, P.L., Clark, P., Hughes, S.H., Janssen, P.A., Arnold, E.
J.Med.Chem.
HeaderTransferase
Released2004-03-27
Resolution2.900
CATH Insert Date05 Mar, 2006

PDB Images (12)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (9)

Domain ID Date inserted into CATH Superfamily CATH Status
1sv5A01 05 Mar, 2006 3.10.10.10 Assigned
1sv5A02 05 Mar, 2006 3.30.70.270 Assigned
1sv5A03 05 Mar, 2006 3.30.70.270 Assigned
1sv5A04 05 Mar, 2006 3.30.70.270 Assigned
1sv5A05 05 Mar, 2006 3.30.420.10 Assigned
1sv5B01 09 Mar, 2006 3.10.10.10 Assigned
1sv5B02 09 Mar, 2006 3.30.70.270 Assigned
1sv5B03 09 Mar, 2006 3.30.70.270 Assigned
1sv5B04 09 Mar, 2006 3.30.70.270 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein