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PDB 1sa5

PDB Information

PDB1SA5
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceRattus norvegicus
Primary Citation
Crystal Structures of the Anticancer Clinical Candidates R115777 (Tipifarnib) and BMS-214662 Complexed with Protein Farnesyltransferase Suggest a Mechanism of FTI Selectivity.
Reid, T.S., Beese, L.S.
Biochemistry
HeaderTransferase
Released2004-02-06
Resolution2.600
CATH Insert Date05 Mar, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1sa5A00 05 Mar, 2006 1.25.40.120 Assigned
1sa5B00 05 Mar, 2006 1.50.10.20 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q02293 FNTB_RAT Rattus norvegicus Protein farnesyltransferase subunit beta
Q04631 FNTA_RAT Rattus norvegicus Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
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