PDB Information

PDB1S9G
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus 1
Primary Citation
Roles of Conformational and Positional Adaptability in Structure-Based Design of TMC125-R165335 (Etravirine) and Related Non-nucleoside Reverse Transcriptase Inhibitors That Are Highly Potent and Effective against Wild-Type and Drug-Resistant HIV-1 Variants.
Das, K., Clark, A.D., Lewi, P.J., Heeres, J., De Jonge, M.R., Koymans, L.M., Vinkers, H.M., Daeyaert, F., Ludovici, D.W., Kukla, M.J., De Corte, B., Kavash, R.W., Ho, C.Y., Ye, H., Lichtenstein, M.A., Andries, K., Pauwels, R., Boyer, P.L., Clark, P., Hughes, S.H., Janssen, P.A., Arnold, E.
J.Med.Chem.
HeaderTransferase
Released2004-02-04
Resolution2.800
CATH Insert Date05 Mar, 2006

PDB Images (12)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (9)

Domain ID Date inserted into CATH Superfamily CATH Status
1s9gA01 05 Mar, 2006 3.10.10.10 Assigned
1s9gA02 05 Mar, 2006 3.30.70.270 Assigned
1s9gA03 05 Mar, 2006 3.30.70.270 Assigned
1s9gA04 05 Mar, 2006 3.30.70.270 Assigned
1s9gA05 05 Mar, 2006 3.30.420.10 Assigned
1s9gB01 09 Mar, 2006 3.10.10.10 Assigned
1s9gB02 09 Mar, 2006 3.30.70.270 Assigned
1s9gB03 09 Mar, 2006 3.30.70.270 Assigned
1s9gB04 09 Mar, 2006 3.30.70.270 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein