PDB Information

PDB1NO6
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Discovery of a Potent, Selective Protein Tyrosine Phosphatase 1B Inhibitor Using a Linked-Fragment Strategy
Szczepankiewicz, B.G., Liu, G., Hajduk, P.J., Abad-Zapatero, C., Pei, Z., Xin, Z., Lubben, T., Trevillyan, J.M., Stashko, M.A., Ballaron, S.J., Liang, H., Huang, F., Hutchins, C.W., Fesik, S.W., Jirousek, M.R.
J.Am.Chem.Soc.
HeaderHydrolase
Released2003-01-15
Resolution2.400
CATH Insert Date05 Mar, 2006

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
1no6A00 05 Mar, 2006 3.90.190.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P18031 PTN1_HUMAN Homo sapiens Tyrosine-protein phosphatase non-receptor type 1