PDB Information

PDB1JTQ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceEscherichia coli
Primary Citation
Multi-targeted antifolates aimed at avoiding drug resistance form covalent closed inhibitory complexes with human and Escherichia coli thymidylate synthases.
Sayre, P.H., Finer-Moore, J.S., Fritz, T.A., Biermann, D., Gates, S.B., MacKellar, W.C., Patel, V.F., Stroud, R.M.
J.Mol.Biol.
HeaderTransferase
Released2001-08-21
Resolution2.500
CATH Insert Date05 Mar, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1jtqA00 05 Mar, 2006 3.30.572.10 Assigned
1jtqB00 05 Mar, 2006 3.30.572.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P0A884 TYSY_ECOLI Escherichia coli K-12 Thymidylate synthase
P0A884 TYSY_ECOLI Escherichia coli K-12 Thymidylate synthase