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PDB Information
| PDB | 1JCS |
| Method | X-RAY DIFFRACTION |
| Host Organism | Spodoptera frugiperda |
| Gene Source | Rattus norvegicus |
| Primary Citation |
The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics.
Long, S.B., Hancock, P.J., Kral, A.M., Hellinga, H.W., Beese, L.S.
Proc.Natl.Acad.Sci.USA
|
| Header | Transferase/Transferase Inhibitor |
| Released | 2001-06-11 |
| Resolution | 2.200 |
| CATH Insert Date | 05 Mar, 2006 |
PDB Images (6)
1jcsA00
CATH Domain 1jcsA00
1jcsB00
CATH Domain 1jcsB00
PDB Chains (3)
| Chain ID | Date inserted into CATH | CATH Status |
| A | 05 Mar, 2006 | Chopped
|
| B | 05 Mar, 2006 | Chopped
|
| C | 05 Mar, 2006 | Rejected
|
CATH Domains (2)
UniProtKB Entries (2)
| Accession |
Gene ID |
Taxon |
Description |
| Q02293 |
FNTB_RAT |
Rattus norvegicus |
Protein farnesyltransferase subunit beta |
| Q04631 |
FNTA_RAT |
Rattus norvegicus |
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha |