PDB Information

PDB1JCQ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics.
Long, S.B., Hancock, P.J., Kral, A.M., Hellinga, H.W., Beese, L.S.
Proc.Natl.Acad.Sci.USA
HeaderTransferase
Released2001-06-11
Resolution2.300
CATH Insert Date05 Mar, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1jcqA00 05 Mar, 2006 1.25.40.120 Assigned
1jcqB00 05 Mar, 2006 1.50.10.20 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P49354 FNTA_HUMAN Homo sapiens Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
P49356 FNTB_HUMAN Homo sapiens Protein farnesyltransferase subunit beta