PDB Information

PDB1I2Z
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceEscherichia coli
Primary Citation
1,4-Disubstituted imidazoles are potential antibacterial agents functioning as inhibitors of enoyl acyl carrier protein reductase (FabI).
Heerding, D.A., Chan, G., DeWolf, W.E., Fosberry, A.P., Janson, C.A., Jaworski, D.D., McManus, E., Miller, W.H., Moore, T.D., Payne, D.J., Qiu, X., Rittenhouse, S.F., Slater-Radosti, C., Smith, W., Takata, D.T., Vaidya, K.S., Yuan, C.C., Huffman, W.F.
Bioorg.Med.Chem.Lett.
HeaderOxidoreductase
Released2001-02-12
Resolution2.800
CATH Insert Date05 Mar, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1i2zA00 05 Mar, 2006 3.40.50.720 Assigned
1i2zB00 05 Mar, 2006 3.40.50.720 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P0AEK4 FABI_ECOLI Escherichia coli K-12 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
P0AEK4 FABI_ECOLI Escherichia coli K-12 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI