PDB 1h1b

PDB Information

PDB1H1B
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Discovery of Further Pyrrolidine Trans-Lactams as Inhibitors of Human Neutrophil Elastase (Hne) with Potential as Development Candidates and the Crystal Structure of Hne Complexed with an Inhibitor (Gw475151)
Macdonald, S.J.F., Dowle, M.D., Harrison, L.A., Clarke, G.D.E., Inglis, G.G.A., Johnson, M.R., Shah, P., Smith, R.A., Amour, A., Fleetwood, G., Humphreys, D.C., Molloy, C.R., Dixon, M., Godward, R.E., Wonacott, A.J., Singh, O.M.P., Hodgson, S.T., Hardy, G.W.
J.Med.Chem.
HeaderHydrolase
Released2002-07-05
Resolution2.000
CATH Insert Date05 Mar, 2006

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
1h1bA01 05 Mar, 2006 2.40.10.10 Assigned
1h1bA02 05 Mar, 2006 2.40.10.10 Assigned
1h1bB01 05 Mar, 2006 2.40.10.10 Assigned
1h1bB02 05 Mar, 2006 2.40.10.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P08246 ELNE_HUMAN Homo sapiens Neutrophil elastase
P08246 ELNE_HUMAN Homo sapiens Neutrophil elastase