PDB 1gfw

PDB Information

PDB1GFW
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Potent and selective nonpeptide inhibitors of caspases 3 and 7 inhibit apoptosis and maintain cell functionality.
Lee, D., Long, S.A., Adams, J.L., Chan, G., Vaidya, K.S., Francis, T.A., Kikly, K., Winkler, J.D., Sung, C.M., Debouck, C., Richardson, S., Levy, M.A., DeWolf Jr., W.E., Keller, P.M., Tomaszek, T., Head, M.S., Ryan, M.D., Haltiwanger, R.C., Liang, P.H., Janson, C.A., McDevitt, P.J., Johanson, K., Concha, N.O., Chan, W., Abdel-Meguid, S.S., Badger, A.M., Lark, M.W., Nadeau, D.P., Suva, L.J., Gowen, M., Nuttall, M.E.
J.Biol.Chem.
HeaderHydrolase
Released2000-06-16
Resolution2.800
CATH Insert Date05 Mar, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1gfwA00 05 Mar, 2006 3.40.50.1460 Assigned
1gfwB00 05 Mar, 2006 3.30.70.1470 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P42574 CASP3_HUMAN Homo sapiens Caspase-3
P42574 CASP3_HUMAN Homo sapiens Caspase-3