PDB Information

PDB1D5X
MethodX-RAY DIFFRACTION
Host OrganismDrosophila melanogaster
Gene SourceHomo sapiens
Primary Citation
Peptide and peptide mimetic inhibitors of antigen presentation by HLA-DR class II MHC molecules. Design, structure-activity relationships, and X-ray crystal structures.
Bolin, D.R., Swain, A.L., Sarabu, R., Berthel, S.J., Gillespie, P., Huby, N.J., Makofske, R., Orzechowski, L., Perrotta, A., Toth, K., Cooper, J.P., Jiang, N., Falcioni, F., Campbell, R., Cox, D., Gaizband, D., Belunis, C.J., Vidovic, D., Ito, K., Crowther, R., Kammlott, U., Zhang, X., Palermo, R., Weber, D., Guenot, J., Nagy, Z., Olson, G.L.
J.Med.Chem.
HeaderImmune System/Peptide Inhibitor
Released1999-10-12
Resolution2.450
CATH Insert Date05 Mar, 2006

PDB Images (11)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Chopped
D 05 Mar, 2006 Rejected

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
1d5xA01 05 Mar, 2006 3.10.320.10 Assigned
1d5xA02 05 Mar, 2006 2.60.40.10 Assigned
1d5xB01 08 Mar, 2006 3.10.320.10 Assigned
1d5xB02 08 Mar, 2006 2.60.40.10 Assigned
1d5xC01 05 Mar, 2006 2.40.50.110 Assigned
1d5xC02 05 Mar, 2006 3.10.20.120 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P01903 DRA_HUMAN Homo sapiens HLA class II histocompatibility antigen, DR alpha chain
P13760 2B14_HUMAN Homo sapiens HLA class II histocompatibility antigen, DRB1-4 beta chain
P01552 ETXB_STAAU Staphylococcus aureus Enterotoxin type B