PDB Information

PDB1AWF
MethodX-RAY DIFFRACTION
Host Organism
Gene SourceHirudo medicinalis
Primary Citation
Novel natural product 5,5-trans-lactone inhibitors of human alpha-thrombin: mechanism of action and structural studies.
Weir, M.P., Bethell, S.S., Cleasby, A., Campbell, C.J., Dennis, R.J., Dix, C.J., Finch, H., Jhoti, H., Mooney, C.J., Patel, S., Tang, C.M., Ward, M., Wonacott, A.J., Wharton, C.W.
Biochemistry
HeaderHydrolase/Hydrolase Inhibitor
Released1997-10-02
Resolution2.200
CATH Insert Date05 Mar, 2006

PDB Images (6)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
H 05 Mar, 2006 Chopped
I 05 Mar, 2006 Rejected
L 05 Mar, 2006 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1awfH01 05 Mar, 2006 2.40.10.10 Assigned
1awfH02 05 Mar, 2006 2.40.10.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P00734 THRB_HUMAN Homo sapiens Prothrombin
P01050 HIRV1_HIRME Hirudo medicinalis Hirudin variant-1
P00734 THRB_HUMAN Homo sapiens Prothrombin