PDB Information

PDB1A81
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structural basis for Syk tyrosine kinase ubiquity in signal transduction pathways revealed by the crystal structure of its regulatory SH2 domains bound to a dually phosphorylated ITAM peptide.
Futterer, K., Wong, J., Grucza, R.A., Chan, A.C., Waksman, G.
J.Mol.Biol.
HeaderComplex (Transferase/Peptide)
Released1998-03-31
Resolution3.000
CATH Insert Date05 Mar, 2006

PDB Images (28)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Rejected
C 05 Mar, 2006 Chopped
D 05 Mar, 2006 Rejected
E 05 Mar, 2006 Chopped
F 05 Mar, 2006 Rejected
G 05 Mar, 2006 Chopped
H 05 Mar, 2006 Rejected
I 05 Mar, 2006 Chopped
J 05 Mar, 2006 Rejected
K 05 Mar, 2006 Chopped
L 05 Mar, 2006 Rejected

CATH Domains (15)

Domain ID Date inserted into CATH Superfamily CATH Status
1a81A01 29 Nov, 2006 3.30.505.10 Assigned
1a81A02 29 Nov, 2006 1.10.930.10 Assigned
1a81A03 29 Nov, 2006 3.30.505.10 Assigned
1a81C01 29 Nov, 2006 3.30.505.10 Assigned
1a81C02 29 Nov, 2006 1.10.930.10 Assigned
1a81C03 29 Nov, 2006 3.30.505.10 Assigned
1a81E01 08 Aug, 2006 3.30.505.10 Assigned
1a81E02 08 Aug, 2006 3.30.505.10 Assigned
1a81G01 28 Nov, 2006 3.30.505.10 Assigned
1a81G02 28 Nov, 2006 3.30.505.10 Assigned
1a81I01 21 Nov, 2006 3.30.505.10 Assigned
1a81I02 21 Nov, 2006 1.10.930.10 Assigned
1a81I03 21 Nov, 2006 3.30.505.10 Assigned
1a81K01 28 Nov, 2006 3.30.505.10 Assigned
1a81K02 28 Nov, 2006 3.30.505.10 Assigned

UniProtKB Entries (12)

Accession Gene ID Taxon Description
P43405 KSYK_HUMAN Homo sapiens Tyrosine-protein kinase SYK
P43405 KSYK_HUMAN Homo sapiens Tyrosine-protein kinase SYK
P07766 CD3E_HUMAN Homo sapiens T-cell surface glycoprotein CD3 epsilon chain
P07766 CD3E_HUMAN Homo sapiens T-cell surface glycoprotein CD3 epsilon chain
P43405 KSYK_HUMAN Homo sapiens Tyrosine-protein kinase SYK
P07766 CD3E_HUMAN Homo sapiens T-cell surface glycoprotein CD3 epsilon chain
P07766 CD3E_HUMAN Homo sapiens T-cell surface glycoprotein CD3 epsilon chain
P07766 CD3E_HUMAN Homo sapiens T-cell surface glycoprotein CD3 epsilon chain
P43405 KSYK_HUMAN Homo sapiens Tyrosine-protein kinase SYK
P43405 KSYK_HUMAN Homo sapiens Tyrosine-protein kinase SYK
P07766 CD3E_HUMAN Homo sapiens T-cell surface glycoprotein CD3 epsilon chain
P43405 KSYK_HUMAN Homo sapiens Tyrosine-protein kinase SYK