The UbiA family of prenyltransferases includes bacterial 4-hydroxybenzoate octaprenyltransferase (gene ubiA); yeast mitochondrial para-hydroxybenzoate--polyprenyltransferase (gene COQ2); protohaem IX farnesyltransferase (haem O synthase) from yeast and mammals (gene COX10), and from bacteria (genes cyoE or ctaB) PMID:8155731,PMID:7885224; and 2-acylphloroglucinol 4-prenyltransferase and 2-acyl-4-prenylphloroglucinol 6-prenyltransferase from plant chloroplasts which catalyze prenylation steps in the beta-bitter acid pathway PMID:22166201,PMID:25564559. These are integral membrane proteins, which probably contain seven transmembrane segments. Archaeal family members include lycopene elongase - this type of enzyme has been shown to be involved in bacterioruberin synthesis in Halobacterium salinarum and Haloferax volcanii PMID:21840984.

INTERPRO:IPR000537