# STOCKHOLM 1.0
#=GF ID 1.10.460.10/FF/000010
#=GF DE DNA topoisomerase 1A
#=GF AC 1.10.460.10/FF/000010
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 33.017
#=GS Q38C52/196-244_580-664      AC Q38C52
#=GS Q38C52/196-244_580-664      OS Trypanosoma brucei brucei TREU927
#=GS Q38C52/196-244_580-664      DE DNA topoisomerase IA, putative
#=GS Q38C52/196-244_580-664      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; 
#=GS Q38C52/196-244_580-664      DR GO; GO:0003677; GO:0003917; GO:0005737; GO:0006265; GO:0006304; 
#=GS Q4QCK3/189-237_565-648      AC Q4QCK3
#=GS Q4QCK3/189-237_565-648      OS Leishmania major
#=GS Q4QCK3/189-237_565-648      DE DNA topoisomerase 1A
#=GS Q4QCK3/189-237_565-648      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; 
#=GS Q4QCK3/189-237_565-648      DR GO; GO:0005737; 
#=GS G0UVI6/196-244_579-669      AC G0UVI6
#=GS G0UVI6/196-244_579-669      OS Trypanosoma congolense IL3000
#=GS G0UVI6/196-244_579-669      DE Putative DNA topoisomerase IA
#=GS G0UVI6/196-244_579-669      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Nannomonas; Trypanosoma congolense; 
#=GS A0A0M9FXS3/188-236_584-666  AC A0A0M9FXS3
#=GS A0A0M9FXS3/188-236_584-666  OS Leptomonas pyrrhocoris
#=GS A0A0M9FXS3/188-236_584-666  DE DNA topoisomerase 1A
#=GS A0A0M9FXS3/188-236_584-666  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leptomonas; Leptomonas pyrrhocoris; 
#=GS A4HBL0/189-237_564-644      AC A4HBL0
#=GS A4HBL0/189-237_564-644      OS Leishmania braziliensis
#=GS A4HBL0/189-237_564-644      DE DNA topoisomerase 1A
#=GS A4HBL0/189-237_564-644      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; 
#=GS A0A0N1PDE4/188-236_583-666  AC A0A0N1PDE4
#=GS A0A0N1PDE4/188-236_583-666  OS Leptomonas seymouri
#=GS A0A0N1PDE4/188-236_583-666  DE DNA topoisomerase 1A
#=GS A0A0N1PDE4/188-236_583-666  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leptomonas; Leptomonas seymouri; 
#=GS A4HZ99/189-237_565-646      AC A4HZ99
#=GS A4HZ99/189-237_565-646      OS Leishmania infantum
#=GS A4HZ99/189-237_565-646      DE DNA topoisomerase 1A
#=GS A4HZ99/189-237_565-646      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum; 
#=GS A0A1E1IVQ2/189-237_564-644  AC A0A1E1IVQ2
#=GS A0A1E1IVQ2/189-237_564-644  OS Leishmania guyanensis
#=GS A0A1E1IVQ2/189-237_564-644  DE Putative DNA topoisomerase 1A
#=GS A0A1E1IVQ2/189-237_564-644  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania guyanensis; 
#=GS E9AUX9/189-237_565-646      AC E9AUX9
#=GS E9AUX9/189-237_565-646      OS Leishmania mexicana MHOM/GT/2001/U1103
#=GS E9AUX9/189-237_565-646      DE DNA topoisomerase 1A
#=GS E9AUX9/189-237_565-646      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania mexicana species complex; Leishmania mexicana; 
#=GS A0A088RPT5/189-237_564-644  AC A0A088RPT5
#=GS A0A088RPT5/189-237_564-644  OS Leishmania panamensis
#=GS A0A088RPT5/189-237_564-644  DE DNA topoisomerase 1A
#=GS A0A088RPT5/189-237_564-644  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania panamensis; 
#=GS E9BF03/189-237_565-646      AC E9BF03
#=GS E9BF03/189-237_565-646      OS Leishmania donovani BPK282A1
#=GS E9BF03/189-237_565-646      DE DNA topoisomerase 1A
#=GS E9BF03/189-237_565-646      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; 
#=GF SQ 11
Q38C52/196-244_580-664              AAETRHVMDRFFGFLGSSVVRAANSQMRSIGRVQTPALILINEREDKISPMPHSEGTLIEELKRNGVGRPSTYPLIVKTLLARGYIQVNAKGRCETTPVGRMLVETAKSTFPSIVDLGFTASFEKQLDTVAKPH------
Q4QCK3/189-237_565-648              AAEARHAMDRIFGFLGSSVVRYANPQMRSIGRVQTPALILINDREDKIK-LPFSEGGLIEQLKNNGVGRPSTYPMIVKTLLARNYITVN-KGRCETTPVGRMLVDTSRATFPSIVDIGFTSAFEKKLDRIAKPR-----S
G0UVI6/196-244_579-669              AAETRHVMDRIFGFLGSSVVRAANSQMRSIGRVQTPALILINEREERIKPMPHSEGTLIEELKRNGVGRPSTYPTIVKTLLARSYIQVNVKGRCETTPLGRMLVETAKSTFPSIVDIGFPASFEKQLDTIAKPNPASQPA
A0A0M9FXS3/188-236_584-666          AAEARHAMDRIFGFLGSSVVRYANPQMRSIGRVQTPALILINDREAKIK-LPYSEGGLIEQLRSNGVGRPSTYPMIVKTLLARNYITVT-RGRCETTPVGRMLVETSRATFPSIVDIGFTAAFEKKLDRIAKPE------
A4HBL0/189-237_564-644              AAEARHAMDRIFGFLGSSVVRYANPQMRSIGRVQTPALILISDREDKIK-LPFSEGGLIEQLKNNGVGRPSTYPMIVKTLLARNYIMVN-KGRCETTPVGRMLVETSRSTFPSIVDIGFTSAFEKKLDRIAK--------
A0A0N1PDE4/188-236_583-666          AAEARHAMDRIFGFLGSSVVRYANPQMRSIGRVQTPALILINDRETKIR-LPYSEGGLIEQLRSNGVGRPSTYPMIVKTLLARNYITVT-RGRCETTPVGRMLVETSRATFPSIVDIGFTAAFEKKLDRIAKPE-----S
A4HZ99/189-237_565-646              AAEARHAMDRIFGFLGSSVVRYANPQMRSIGRVQTPALILIKDREDKIK-LPFSEGGLIEQLKNNGVGRPSTYPMIVKTLLARNYITVK-KGRCETTPVGRMLVDTSRATFPSIVDIGFTSAFEKKLDRIAKP-------
A0A1E1IVQ2/189-237_564-644          AAEARHAMDRIFGFLGSSVVRYANPQMRSIGRVQTPALILISDREDKIK-LPFSEGGLIEQLKNNGVGRPSTYPMIVKTLLARNYIMVN-KGRCETTPVGRMLVETSRSTFPSIVDIGFTSAFEKKLDRIAK--------
E9AUX9/189-237_565-646              AAEARHAMDRIFGFLGSSVVRYANPQMRSIGRVQTPALILINDREDKIK-LPFSEGGLIEQLKNNGVGRPSTYPMIVKTLLARNYITVN-KGRCETTPVGRMLVDTSRATFPSIVDIGFTSAFEKKLDRIAKP-------
A0A088RPT5/189-237_564-644          AAEARHAMDRIFGFLGSSVVRYANPQMRSIGRVQTPALILISDREDKIK-LPFSEGGLIEQLKNNGVGRPSTYPMIVKTLLARNYIMVN-KGRCETTPVGRMLVETSRSTFPSIVDIGFTSAFEKKLDRIAK--------
E9BF03/189-237_565-646              AAEARHAMDRIFGFLGSSVVRYANPQMRSIGRVQTPALILIKDREDKIK-LPFSEGGLIEQLKNNGVGRPSTYPMIVKTLLARNYITVK-KGRCETTPVGRMLVDTSRATFPSIVDIGFTSAFEKKLDRIAKP-------
#=GC scorecons                      99969969997999999999949969999999999999999579957960695999599969749999999999599999999599496079999999799999796769999999799756999699579951000000
#=GC scorecons_70                   ******_**************_**_****************_***_***_**_***_******_**********_********_**_*__****************_*_***********__******_***________
#=GC scorecons_80                   ***_**_***_**********_**_****************__**_**___*_***_***_**_**********_********_**_*__****************___**********___***_**_***________
#=GC scorecons_90                   ***_**_***_**********_**_****************__**__*___*_***_***_*__**********_********_**_*___*******_*****_*___*******_**___***_**__**________
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