# STOCKHOLM 1.0
#=GF ID 3.40.710.10/FF/000095
#=GF DE Penicillin-binding protein 2x
#=GF AC 3.40.710.10/FF/000095
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 24.122
#=GS 2zc4E00/1-385       AC P14677
#=GS 2zc4E00/1-385       OS Streptococcus pneumoniae TIGR4
#=GS 2zc4E00/1-385       DE Penicillin-binding protein 2x
#=GS 2zc4E00/1-385       DR CATH; 2zc4; E:254-620; 
#=GS 2zc4E00/1-385       DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; 
#=GS 2zc4B00/1-385       AC P14677
#=GS 2zc4B00/1-385       OS Streptococcus pneumoniae TIGR4
#=GS 2zc4B00/1-385       DE Penicillin-binding protein 2x
#=GS 2zc4B00/1-385       DR CATH; 2zc4; B:254-619; 
#=GS 2zc4B00/1-385       DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; 
#=GS 2zc3E00/1-385       AC P14677
#=GS 2zc3E00/1-385       OS Streptococcus pneumoniae TIGR4
#=GS 2zc3E00/1-385       DE Penicillin-binding protein 2x
#=GS 2zc3E00/1-385       DR CATH; 2zc3; E:254-620; 
#=GS 2zc3E00/1-385       DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; 
#=GS 2zc3B00/1-385       AC P14677
#=GS 2zc3B00/1-385       OS Streptococcus pneumoniae TIGR4
#=GS 2zc3B00/1-385       DE Penicillin-binding protein 2x
#=GS 2zc3B00/1-385       DR CATH; 2zc3; B:254-619; 
#=GS 2zc3B00/1-385       DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; 
#=GS 2z2mE00/1-385       AC P14677
#=GS 2z2mE00/1-385       OS Streptococcus pneumoniae TIGR4
#=GS 2z2mE00/1-385       DE Penicillin-binding protein 2x
#=GS 2z2mE00/1-385       DR CATH; 2z2m; E:254-620; 
#=GS 2z2mE00/1-385       DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; 
#=GS 2z2mB00/1-385       AC P14677
#=GS 2z2mB00/1-385       OS Streptococcus pneumoniae TIGR4
#=GS 2z2mB00/1-385       DE Penicillin-binding protein 2x
#=GS 2z2mB00/1-385       DR CATH; 2z2m; B:254-620; 
#=GS 2z2mB00/1-385       DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; 
#=GS 2z2lE00/1-385       AC P14677
#=GS 2z2lE00/1-385       OS Streptococcus pneumoniae TIGR4
#=GS 2z2lE00/1-385       DE Penicillin-binding protein 2x
#=GS 2z2lE00/1-385       DR CATH; 2z2l; E:254-620; 
#=GS 2z2lE00/1-385       DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; 
#=GS 2z2lB00/1-385       AC P14677
#=GS 2z2lB00/1-385       OS Streptococcus pneumoniae TIGR4
#=GS 2z2lB00/1-385       DE Penicillin-binding protein 2x
#=GS 2z2lB00/1-385       DR CATH; 2z2l; B:254-620; 
#=GS 2z2lB00/1-385       DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; 
#=GS 1rp5B04/209-579     AC P14677
#=GS 1rp5B04/209-579     OS Streptococcus pneumoniae TIGR4
#=GS 1rp5B04/209-579     DE Penicillin-binding protein 2x
#=GS 1rp5B04/209-579     DR CATH; 1rp5; B:257-627; 
#=GS 1rp5B04/209-579     DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; 
#=GS 1rp5A04/209-579     AC P14677
#=GS 1rp5A04/209-579     OS Streptococcus pneumoniae TIGR4
#=GS 1rp5A04/209-579     DE Penicillin-binding protein 2x
#=GS 1rp5A04/209-579     DR CATH; 1rp5; A:257-627; 
#=GS 1rp5A04/209-579     DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; 
#=GS 1qmfA02/216-432_447-572 AC P14677
#=GS 1qmfA02/216-432_447-572 OS Streptococcus pneumoniae TIGR4
#=GS 1qmfA02/216-432_447-572 DE Penicillin-binding protein 2x
#=GS 1qmfA02/216-432_447-572 DR CATH; 1qmf; A:264-480; A:495-620; 
#=GS 1qmfA02/216-432_447-572 DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; 
#=GS 1qmeA02/216-432_447-573 AC P14677
#=GS 1qmeA02/216-432_447-573 OS Streptococcus pneumoniae TIGR4
#=GS 1qmeA02/216-432_447-573 DE Penicillin-binding protein 2x
#=GS 1qmeA02/216-432_447-573 DR CATH; 1qme; A:264-480; A:495-632; 
#=GS 1qmeA02/216-432_447-573 DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; 
#=GS 1pyyA02/216-579     AC P59676
#=GS 1pyyA02/216-579     OS Streptococcus pneumoniae R6
#=GS 1pyyA02/216-579     DE Penicillin-binding protein 2X
#=GS 1pyyA02/216-579     DR CATH; 1pyy; A:264-627; 
#=GS 1pyyA02/216-579     DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; 
#=GS Q9Z9X4/10-111       AC Q9Z9X4
#=GS Q9Z9X4/10-111       OS Streptococcus pneumoniae
#=GS Q9Z9X4/10-111       DE Penicillin binding protein 2X
#=GS Q9Z9X4/10-111       DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; 
#=GS B9V3Y5/165-269      AC B9V3Y5
#=GS B9V3Y5/165-269      OS Streptococcus pneumoniae
#=GS B9V3Y5/165-269      DE Penicillin-binding protein 2X
#=GS B9V3Y5/165-269      DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; 
#=GS Q4U0W4/26-130       AC Q4U0W4
#=GS Q4U0W4/26-130       OS Streptococcus pneumoniae
#=GS Q4U0W4/26-130       DE Penicillin-binding protein 2x
#=GS Q4U0W4/26-130       DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; 
#=GS A0A0H2ZRH4/265-369  AC A0A0H2ZRH4
#=GS A0A0H2ZRH4/265-369  OS Streptococcus pneumoniae D39
#=GS A0A0H2ZRH4/265-369  DE Penicillin-binding protein 2X
#=GS A0A0H2ZRH4/265-369  DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; 
#=GS P59676/265-369      AC P59676
#=GS P59676/265-369      OS Streptococcus pneumoniae R6
#=GS P59676/265-369      DE Penicillin-binding protein 2X
#=GS P59676/265-369      DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; 
#=GS A0A0E8T757/265-369  AC A0A0E8T757
#=GS A0A0E8T757/265-369  OS Streptococcus pneumoniae
#=GS A0A0E8T757/265-369  DE Penicillin-binding protein 2X
#=GS A0A0E8T757/265-369  DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; 
#=GF SQ 19
2zc4E00/1-385               LGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAK--
2zc4B00/1-385               LGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAK--
2zc3E00/1-385               LGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAK--
2zc3B00/1-385               LGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAK--
2z2mE00/1-385               LGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAK--
2z2mB00/1-385               LGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAK--
2z2lE00/1-385               LGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAK--
2z2lB00/1-385               LGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAK--
1rp5B04/209-579             ----------------DGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAMSAFGQGISVTQTQMLRAFTAIANDGVMLEPKFISALYDPNDQSVRKSQKEIVGNPVSKEAASVTRDHMVMVGTDPTYGTMYNHSTGKATVNVPGQNVALKSGTAEIADEKNGGYLTGSTNNIFSVVSMHPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKESLNLQTTAKAL
1rp5A04/209-579             ----------------DGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAMSAFGQGISVTQTQMLRAFTAIANDGVMLEPKFISALYDPNDQSVRKSQKEIVGNPVSKEAASVTRDHMVMVGTDPTYGTMYNHSTGKATVNVPGQNVALKSGTAEIADEKNGGYLTGSTNNIFSVVSMHPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKESLNLQTTAKAL
1qmfA02/216-432_447-572     -----------------------TISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFI--------------QKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNL-------
1qmeA02/216-432_447-573     -----------------------TISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFI--------------QKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQ------
1pyyA02/216-579             -----------------------TISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSAFKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKAL
Q9Z9X4/10-111               ------------------------ISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITKDFVWRDILYQSNYEPGSTMKVMTLAAAIDNNTFPGGEVFDSSELKI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
B9V3Y5/165-269              ------------------------ISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q4U0W4/26-130               ------------------------ISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSAMKVMMLAAAIDNNTFPGGEVFNSSELKIADA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A0A0H2ZRH4/265-369          ------------------------ISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P59676/265-369              ------------------------ISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A0A0E8T757/265-369          ------------------------ISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
#=GC scorecons              000000000000000011111112999999999999999999999999999999999999999999999999999999989999999999999999978999899999999999999998999999777222222222222222222222222222222222222222222222222222222222222222222222222222221222222222222222222222222222222222111111111111112222222222222222221222222222222222222222222222222222222222222222222222122122222221222222222222222222222222222222222222222222222111100
#=GC scorecons_70           ________________________*********************************************************************************************************__________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________
#=GC scorecons_80           ________________________*********************************************************************************************************__________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________
#=GC scorecons_90           ________________________*************************************************************************_****_***********************_____________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________
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