# STOCKHOLM 1.0 #=GF ID 3.40.50.2020/FF/000058 #=GF DE Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase #=GF AC 3.40.50.2020/FF/000058 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 89.795 #=GS 3qw4C02/254-453 AC E9BCQ9 #=GS 3qw4C02/254-453 OS Leishmania donovani BPK282A1 #=GS 3qw4C02/254-453 DE Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative #=GS 3qw4C02/254-453 DR CATH; 3qw4; C:253-452; #=GS 3qw4C02/254-453 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; #=GS Q8ZTG3/1-192 AC Q8ZTG3 #=GS Q8ZTG3/1-192 OS Pyrobaculum aerophilum str. IM2 #=GS Q8ZTG3/1-192 DE Orotate phosphoribosyltransferase #=GS Q8ZTG3/1-192 DR ORG; Archaea; Crenarchaeota; Thermoprotei; Thermoproteales; Thermoproteaceae; Pyrobaculum; Pyrobaculum aerophilum; #=GS Q8ZTG3/1-192 DR EC; 2.4.2.10; #=GS Q57U85/254-457 AC Q57U85 #=GS Q57U85/254-457 OS Trypanosoma brucei brucei TREU927 #=GS Q57U85/254-457 DE Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative #=GS Q57U85/254-457 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; #=GS Q57U85/254-457 DR GO; GO:0004588; GO:0009220; GO:0020015; #=GS Q9UX09/1-194 AC Q9UX09 #=GS Q9UX09/1-194 OS Saccharolobus solfataricus P2 #=GS Q9UX09/1-194 DE Orotate phosphoribosyltransferase #=GS Q9UX09/1-194 DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Saccharolobus; Saccharolobus solfataricus; #=GS Q9UX09/1-194 DR EC; 2.4.2.10; #=GS A9A401/1-201 AC A9A401 #=GS A9A401/1-201 OS Nitrosopumilus maritimus SCM1 #=GS A9A401/1-201 DE Orotate phosphoribosyltransferase #=GS A9A401/1-201 DR ORG; Archaea; Thaumarchaeota; Nitrosopumilales; Nitrosopumilaceae; Nitrosopumilus; Nitrosopumilus maritimus; #=GS B1L386/3-191 AC B1L386 #=GS B1L386/3-191 OS Candidatus Korarchaeum cryptofilum OPF8 #=GS B1L386/3-191 DE Orotate phosphoribosyltransferase #=GS B1L386/3-191 DR ORG; Archaea; Candidatus Korarchaeota; Candidatus Korarchaeum; Candidatus Korarchaeum cryptofilum; #=GS 3qw4B02/254-453 AC E9BCQ9 #=GS 3qw4B02/254-453 OS Leishmania donovani BPK282A1 #=GS 3qw4B02/254-453 DE Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative #=GS 3qw4B02/254-453 DR CATH; 3qw4; B:253-452; #=GS 3qw4B02/254-453 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; #=GS A0A0M9FX33/255-452 AC A0A0M9FX33 #=GS A0A0M9FX33/255-452 OS Leptomonas pyrrhocoris #=GS A0A0M9FX33/255-452 DE Putative orotidine-5-phosphate decarboxylase #=GS A0A0M9FX33/255-452 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leptomonas; Leptomonas pyrrhocoris; #=GS A0A088RNV2/255-452 AC A0A088RNV2 #=GS A0A088RNV2/255-452 OS Leishmania panamensis #=GS A0A088RNV2/255-452 DE Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative #=GS A0A088RNV2/255-452 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania panamensis; #=GS C9ZPR2/254-457 AC C9ZPR2 #=GS C9ZPR2/254-457 OS Trypanosoma brucei gambiense DAL972 #=GS C9ZPR2/254-457 DE Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative #=GS C9ZPR2/254-457 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei gambiense; #=GS A0A3L6L6X3/254-457 AC A0A3L6L6X3 #=GS A0A3L6L6X3/254-457 OS Trypanosoma brucei equiperdum #=GS A0A3L6L6X3/254-457 DE Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase #=GS A0A3L6L6X3/254-457 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei equiperdum; #=GS Q4QEW5/255-452 AC Q4QEW5 #=GS Q4QEW5/255-452 OS Leishmania major #=GS Q4QEW5/255-452 DE Putative OMPDCase-OPRTase #=GS Q4QEW5/255-452 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; #=GS A4H8I0/255-452 AC A4H8I0 #=GS A4H8I0/255-452 OS Leishmania braziliensis #=GS A4H8I0/255-452 DE Putative orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase #=GS A4H8I0/255-452 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; #=GS E9AQL3/255-452 AC E9AQL3 #=GS E9AQL3/255-452 OS Leishmania mexicana MHOM/GT/2001/U1103 #=GS E9AQL3/255-452 DE Putative orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase (Putative ompdcase-oprtase) #=GS E9AQL3/255-452 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania mexicana species complex; Leishmania mexicana; #=GS A4HWV2/255-452 AC A4HWV2 #=GS A4HWV2/255-452 OS Leishmania infantum #=GS A4HWV2/255-452 DE Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase #=GS A4HWV2/255-452 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum; #=GS H9ABT8/255-452 AC H9ABT8 #=GS H9ABT8/255-452 OS Leishmania donovani #=GS H9ABT8/255-452 DE Orotidine monophosphate decarboxylase-orotate phosphoribosyltransferase #=GS H9ABT8/255-452 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; #=GS E9BCQ9/255-452 AC E9BCQ9 #=GS E9BCQ9/255-452 OS Leishmania donovani BPK282A1 #=GS E9BCQ9/255-452 DE Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative #=GS E9BCQ9/255-452 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; #=GS A0A3P3Z2I2/255-452 AC A0A3P3Z2I2 #=GS A0A3P3Z2I2/255-452 OS Leishmania braziliensis MHOM/BR/75/M2904 #=GS A0A3P3Z2I2/255-452 DE Orotidine-5-phosphate_decarboxylase/orotate_phosp horibosyltransferase #=GS A0A3P3Z2I2/255-452 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; #=GS A0A0E3GTK0/1-194 AC A0A0E3GTK0 #=GS A0A0E3GTK0/1-194 OS Saccharolobus solfataricus #=GS A0A0E3GTK0/1-194 DE Orotate phosphoribosyltransferase #=GS A0A0E3GTK0/1-194 DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Saccharolobus; Saccharolobus solfataricus; #=GS A0A0E3GTK0/1-194 DR EC; 2.4.2.10; #=GS D0KT27/1-194 AC D0KT27 #=GS D0KT27/1-194 OS Saccharolobus solfataricus 98/2 #=GS D0KT27/1-194 DE Orotate phosphoribosyltransferase #=GS D0KT27/1-194 DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Saccharolobus; Saccharolobus solfataricus; #=GS D0KT27/1-194 DR EC; 2.4.2.10; #=GF SQ 20 3qw4C02/254-453 -FAKGASVELAKALVDSHCVRFGNFTLKSGKSSPIYIDLRRLVTYPAIMRLVAREYAKVLRH----YKFDRIAGLPYAALPIASAISNEMNVPLIYPRREAKIYGTKAAIEGEYKKGDRVVIIDDLVSTGETKVEAIEKLRSAGLEVVSIVVLVDR-DMGAKAFLNKLGYDFEAVVGLHQLLPLWRKSNAITSQQEADVRAFLGQW--- Q8ZTG3/1-192 ---------MIKRLVDIGAVKFGAFKLSSGLESPFYVDLRSVLGEPELFQWVIERYEAVLSG----LEFDVIIGVATGGIPYASVLGYRLKKPMGYVRDEAKGYGTGRQIEGADVAGKRAAVVDDVLTTGKSVLNAIRAVRASGGEVAGVVVFLDRGQCGAEAVKREAGVYVYSVYKMRELLEELR--PHIGEERYRSVLDYLSQWR-- Q57U85/254-457 RLRTNNVSEMAGALVASQCVRFGKFTLKSGKTSPIYIDLRRLVTHPLIMRLVARHYARILTT----MQFDRIVGLPYAALPIATAISLEMNVPLIYPRRERKDYGTKGLIEGDFQKGDRVVIVDDLVTTGETKVEAIEKLKAAGLHIVSIVVLIDR-EMGAKKFLGSLGYEFHAVATLSQLLPLWLQQGAITDKQMREVTAFMLESTSK Q9UX09/1-194 -------MNFAEVLLERKLLLIGSFVLTSGKVSPYYLDLRPLPNYPEFYDIVNQAIKKA-KD----IPHDIIVGIATGGVPLSAFIACNLKEPMGYIRIEKKGHGTNRTLELDV-KGKRVLLVDDVATTGVSIEKATLEILNGGGKVSDALVIIDR-QEGASQRLEKLGVKLHSLFKISEILDELLKSDKLKDNEKKSILDYLVKNVE- A9A401/1-201 ---MEFVKEFATFLHQKGIIKFGDFTLASGKKSSYYVDLRLVPSYPQEFRKMVKYLENEIAQNIGLDKFDSIVSVPTGGLVIASALAIETVKPLIYVRSKPKDYGTSKSVEGKIHDGMQVVMIDDVATTGGSVVNAIKSLKEVNISVKDAYVIVNR-MEGADEALNELDVKMHSILNILQITEALHEQNLVDDEILEKVKNQIAK---- B1L386/3-191 ------AHELGIILISRGMLKFGEFTLTSGKKSNIYVDLRPLPSFPEEFMKIATEMSKRMNGDFG------ICGVAVGGLPLATAVAIISRRPLIYVRKEKKEHGTESLLEGSL-NMRSYVIIDDVATTGGSILNAARIVRNYGPDVKEAWVVVDR-MQGAAESLKEEGIELKSLATLPDIVKLVL--DSLPERERSYALKYLGE---- 3qw4B02/254-453 -FAKGASVELAKALVDSHCVRFGNFTLKSGKSSPIYIDLRRLVTYPAIMRLVAREYAKVLRH----YKFDRIAGLPYAALPIASAISNEMNVPLIYPRREAKIYGTKAAIEGEYKKGDRVVIIDDLVSTGETKVEAIEKLRSAGLEVVSIVVLVDR-DMGAKAFLNKLGYDFEAVVGLHQLLPLWRKSNAITSQQEADVRAFLGQW--- A0A0M9FX33/255-452 ---KGASTELATALVESHCVRFGTFTLKSGKTSPIYIDLRRLVTYPSIMRLVAREYAKVLRQ----YKFDRIAGLPYAALPIASAISNEMNVPLIYPRREAKSYGTKAAIEGEYKKGDRVVIIDDLVSTGETKVEAIDKLKSAGLEVVAIVVLVDR-EMGAKAFLNGLGYEFEAVVGLYQLLPLWRKSNAITAAQEAEVRAFLGQW--- A0A088RNV2/255-452 ---KGASVELAKALVDSHCVRFGNFMLKSGKSSPIYIDLRLLVTYPTIMRLVAREYAKVLRH----YKFDRIAGLPYAALPIASAISNEMNVPLIYPRREAKSYGTKASIEGEYKKGDRVVIIDDLVSTGETKVEAIEKLKSAGLEVVSIVVLVDR-EMGAKAFLNKLGYDFEAVVGLYQLLPLWRQSNAMTSQQEADVRAFLGQW--- C9ZPR2/254-457 RLRTNNVSEMAGALVASQCVRFGKFTLKSGKTSPIYIDLRRLVTHPLIMRLVARHYARILTT----MQFDRIVGLPYAALPIATAISLEMNVPLIYPRRERKDYGTKGLIEGDFQKGDRVVIVDDLVTTGETKVEAIEKLKAAGLHIVSIVVLIDR-EMGAKKFLGSLGYEFHAVATLSQLLPLWLQQGAITDKQMREVTAFMLESTSK A0A3L6L6X3/254-457 RLRTNNVSEMAGALVASQCVRFGKFTLKSGKTSPIYIDLRRLVTHPLIMRLVARHYARILTT----MQFDRIVGLPYAALPIATAISLEMNVPLIYPRRERKDYGTKGLIEGDFQKGDRVVIVDDLVTTGETKVEAIEKLKAAGLHIVSIVVLIDR-EMGAKKFLGSLGYEFHAVATLSQLLPLWLQQGAITDKQMREVTAFMLESTSK Q4QEW5/255-452 ---KGASVELAKALVDSHCVRFGNFTLKSGKSSPIYIDLRRLVTYPAIMRLVAREYAKVLRH----YKFDRIAGLPYAALPIASAISNEMNVPLIYPRREAKIYGTKAAIEGEYKKGDRVVIIDDLVSTGETKVEAIEKLRSAGLEVVSIVVLVDR-DMGAKAFLSKLGYDFEAVVGLHQLLPLWRKSNAITSQQEADVRAFLGQW--- A4H8I0/255-452 ---KGASVELAKALVDSHCVRFGNFMLKSGKSSPIYIDLRLLVTYPTIMRLVAREYAKVLRH----YKFDRIAGLPYAALPIASAISNEMNVPLIYPRREAKSYGTKASIEGEYKKGDRVVIIDDLVSTGETKVEAIEKLKSAGLEVVSIVVLVDR-EMGAKAFLNKLGYDFEAVVGLYQLLPLWRQSNAMTSQQEADVRAFLGQW--- E9AQL3/255-452 ---KGASVELAKALVDSHCVRFGNFTLKSGKSSPIYIDLRRLVTYPAIMRLVAREYAKVLRH----YKFDRIAGLPYAALPIASAISNEMNVPLIYPRREAKIYGTKAAIEGEYKKGDRVVIIDDLVSTGETKVEAIEKLRSAGLEVVSIVVLVDR-DMGAKAFLNKLGYDFEAVVGLHQLLPLWRKSNAITSQQEADVRAFLGQW--- A4HWV2/255-452 ---KGASVELAKALVDSHCVRFGNFTLKSGKSSPIYIDLRRLVTYPAIMRLVAREYAKVLRH----YKFDRIAGLPYAALPIASAISNEMNVPLIYPRREAKIYGTKAAIEGEYKKGDRVVIIDDLVSTGETKVEAIEKLRSAGLEVVSIVVLVDR-DMGAKAFLNKLGYDFEAVVGLHQLLPLWRKSNAITSQQEADVRAFLGQW--- H9ABT8/255-452 ---KGASVELAKALVDSHCVRFGNFTLKSGKSSPIYIDLRRLVTYPAIMRLVAREYAKVLRH----YKFDRIAGLPYAALPIASAISNEMNVPLIYPRREAKIYGTKAAIEGEYKKGDRVVIIDDLVSTGETKVEAIEKLRSAGLEVVSIVVLVDR-DMGAKAFLNKLGYDFEAVVGLHQLLPLWRKSNAITSQQEADVRAFLGQW--- E9BCQ9/255-452 ---KGASVELAKALVDSHCVRFGNFTLKSGKSSPIYIDLRRLVTYPAIMRLVAREYAKVLRH----YKFDRIAGLPYAALPIASAISNEMNVPLIYPRREAKIYGTKAAIEGEYKKGDRVVIIDDLVSTGETKVEAIEKLRSAGLEVVSIVVLVDR-DMGAKAFLNKLGYDFEAVVGLHQLLPLWRKSNAITSQQEADVRAFLGQW--- A0A3P3Z2I2/255-452 ---KGASVELAKALVDSHCVRFGNFMLKSGKSSPIYIDLRLLVTYPTIMRLVAREYAKVLRH----YKFDRIAGLPYAALPIASAISNEMNVPLIYPRREAKSYGTKASIEGEYKKGDRVVIIDDLVSTGETKVEAIEKLKSAGLEVVSIVVLVDR-EMGAKAFLNKLGYDFEAVVGLYQLLPLWRQSNAMTSQQEADVRAFLGQW--- A0A0E3GTK0/1-194 -------MNFAEVLLERKLLLIGSFVLTSGKVSPYYLDLRPLPNYPEFYDIVNQAIKKA-KD----IPHDIIVGIATGGVPLSAFIACNLKEPMGYIRIEKKGHGTNRTLELDV-KGKRVLLVDDVATTGVSIEKATLEILNGGGKVSDALVIIDR-QEGASQRLEKLGVKLHSLFKISEILDELLKSDKLKDNEKKSILDYLVKNVE- D0KT27/1-194 -------MNFAEVLLERKLLLIGSFVLTSGKVSPYYLDLRPLPNYPEFYDIVNQAIKKA-KD----IPHDIIVGIATGGVPLSAFIACNLKEPMGYIRIEKKGHGTNRTLELDV-KGKRVLLVDDVATTGVSIEKATLEILNGGGKVSDALVIIDR-QEGASQRLEKLGVKLHSLFKISEILDELLKSDKLKDNEKKSILDYLVKNVE- #=GC scorecons 00012123557449544446569495949973975969994755693455475544464444000033573958664666756557535554975949484937995436955326747666799656994645596446444844845559568904499443745684455664463667444444545454534464467452000 #=GC scorecons_70 __________*__*_____*_**_*_*_***_**_*_***_*__**_____*_____*___________*_*_*_____**_*__*______**_*_*_*_*_***___**____**_********__**_____*_______*__*____*_***___**___*__**_____*__*__**________________*__**______ #=GC scorecons_80 __________*__*________*_*_*_***_*__*_***_*___*_____*_________________*_*_*______*___________*__*_*_*_*_***____*_____*_*____**___**_____*_______*__*____*__**___**___*___*____________*____________________*______ #=GC scorecons_90 _____________*________*_*_*_**__*__*_***_____*_________________________*_*__________________*__*_*_*_*__**____*____________**___**_____*_______________*__**___**_______*________________________________________ //