# STOCKHOLM 1.0 #=GF ID 3.40.50.150/FF/000207 #=GF DE Leucine carboxyl methyltransferase 2 #=GF AC 3.40.50.150/FF/000207 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 89.623 #=GS O60294/3-323 AC O60294 #=GS O60294/3-323 OS Homo sapiens #=GS O60294/3-323 DE tRNA wybutosine-synthesizing protein 4 #=GS O60294/3-323 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; #=GS O60294/3-323 DR GO; GO:0005515; GO:0005737; GO:0006400; GO:0008175; #=GS O60294/3-323 DR EC; 2.1.1.290; 2.3.1.231; #=GS Q8BYR1/3-315 AC Q8BYR1 #=GS Q8BYR1/3-315 OS Mus musculus #=GS Q8BYR1/3-315 DE tRNA wybutosine-synthesizing protein 4 #=GS Q8BYR1/3-315 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Myomorpha; Muridae; Murinae; Mus; Mus; Mus musculus; #=GS Q8BYR1/3-315 DR GO; GO:0003880; GO:0006481; #=GS Q8BYR1/3-315 DR EC; 2.1.1.290; 2.3.1.231; #=GS W4XPM5/2-327 AC W4XPM5 #=GS W4XPM5/2-327 OS Strongylocentrotus purpuratus #=GS W4XPM5/2-327 DE Uncharacterized protein #=GS W4XPM5/2-327 DR ORG; Eukaryota; Metazoa; Echinodermata; Echinozoa; Echinoidea; Euechinoidea; Echinacea; Echinoida; Strongylocentrotidae; Strongylocentrotus; Strongylocentrotus purpuratus; #=GS W4YET6/2-329 AC W4YET6 #=GS W4YET6/2-329 OS Strongylocentrotus purpuratus #=GS W4YET6/2-329 DE Uncharacterized protein #=GS W4YET6/2-329 DR ORG; Eukaryota; Metazoa; Echinodermata; Echinozoa; Echinoidea; Euechinoidea; Echinacea; Echinoida; Strongylocentrotidae; Strongylocentrotus; Strongylocentrotus purpuratus; #=GS E9G924/1-295 AC E9G924 #=GS E9G924/1-295 OS Daphnia pulex #=GS E9G924/1-295 DE Uncharacterized protein #=GS E9G924/1-295 DR ORG; Eukaryota; Metazoa; Arthropoda; Crustacea; Branchiopoda; Phyllopoda; Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia; Daphnia pulex; #=GS A7S1F7/1-304 AC A7S1F7 #=GS A7S1F7/1-304 OS Nematostella vectensis #=GS A7S1F7/1-304 DE Predicted protein #=GS A7S1F7/1-304 DR ORG; Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria; Edwardsiidae; Nematostella; Nematostella vectensis; #=GS A9V7T0/16-172_216-386 AC A9V7T0 #=GS A9V7T0/16-172_216-386 OS Monosiga brevicollis #=GS A9V7T0/16-172_216-386 DE Predicted protein #=GS A9V7T0/16-172_216-386 DR ORG; Eukaryota; Choanoflagellida; Salpingoecidae; Monosiga; Monosiga brevicollis; #=GS F6X2Y1/2-319 AC F6X2Y1 #=GS F6X2Y1/2-319 OS Ciona intestinalis #=GS F6X2Y1/2-319 DE tRNA wybutosine-synthesizing protein 4 #=GS F6X2Y1/2-319 DR ORG; Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Enterogona; Phlebobranchia; Cionidae; Ciona; Ciona intestinalis; #=GS B7PPL2/3-309 AC B7PPL2 #=GS B7PPL2/3-309 OS Ixodes scapularis #=GS B7PPL2/3-309 DE Carboxymethyl transferase, putative #=GS B7PPL2/3-309 DR ORG; Eukaryota; Metazoa; Arthropoda; Chelicerata; Arachnida; Acari; Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes; Ixodes scapularis; #=GS A0A2R8PXN4/2-306 AC A0A2R8PXN4 #=GS A0A2R8PXN4/2-306 OS Danio rerio #=GS A0A2R8PXN4/2-306 DE Leucine carboxyl methyltransferase 2 #=GS A0A2R8PXN4/2-306 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Otomorpha; Ostariophysi; Cypriniphysae; Cypriniformes; Cyprinoidei; Cyprinidae; Danio; Danio rerio; #=GS E1C573/5-319 AC E1C573 #=GS E1C573/5-319 OS Gallus gallus #=GS E1C573/5-319 DE Uncharacterized protein #=GS E1C573/5-319 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus; Gallus gallus; #=GS A0A2U3VAL4/3-323 AC A0A2U3VAL4 #=GS A0A2U3VAL4/3-323 OS Tursiops truncatus #=GS A0A2U3VAL4/3-323 DE tRNA wybutosine-synthesizing protein 4 #=GS A0A2U3VAL4/3-323 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Cetacea; Odontoceti; Delphinidae; Tursiops; Tursiops truncatus; #=GS A0A452DQ16/2-323 AC A0A452DQ16 #=GS A0A452DQ16/2-323 OS Capra hircus #=GS A0A452DQ16/2-323 DE Uncharacterized protein #=GS A0A452DQ16/2-323 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Ruminantia; Pecora; Bovidae; Caprinae; Capra; Capra hircus; #=GS A0A3Q7U5X8/3-323 AC A0A3Q7U5X8 #=GS A0A3Q7U5X8/3-323 OS Ursus arctos horribilis #=GS A0A3Q7U5X8/3-323 DE tRNA wybutosine-synthesizing protein 4 #=GS A0A3Q7U5X8/3-323 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus; Ursus arctos; Ursus arctos horribilis; #=GS F1SI58/3-323 AC F1SI58 #=GS F1SI58/3-323 OS Sus scrofa #=GS F1SI58/3-323 DE Uncharacterized protein #=GS F1SI58/3-323 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Suina; Suidae; Sus; Sus scrofa; #=GS W5M959/19-337 AC W5M959 #=GS W5M959/19-337 OS Lepisosteus oculatus #=GS W5M959/19-337 DE Leucine carboxyl methyltransferase 2 #=GS W5M959/19-337 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Holostei; Semionotiformes; Lepisosteidae; Lepisosteus; Lepisosteus oculatus; #=GS A0A383ZEY6/3-323 AC A0A383ZEY6 #=GS A0A383ZEY6/3-323 OS Balaenoptera acutorostrata scammoni #=GS A0A383ZEY6/3-323 DE tRNA wybutosine-synthesizing protein 4 #=GS A0A383ZEY6/3-323 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Cetacea; Mysticeti; Balaenopteridae; Balaenoptera; Balaenoptera acutorostrata; Balaenoptera acutorostrata scammoni; #=GS A0A340YIG7/3-323 AC A0A340YIG7 #=GS A0A340YIG7/3-323 OS Lipotes vexillifer #=GS A0A340YIG7/3-323 DE LOW QUALITY PROTEIN: leucine carboxyl methyltransferase 2 #=GS A0A340YIG7/3-323 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Cetacea; Odontoceti; Lipotidae; Lipotes; Lipotes vexillifer; #=GS A0A2F0B8D2/3-323 AC A0A2F0B8D2 #=GS A0A2F0B8D2/3-323 OS Eschrichtius robustus #=GS A0A2F0B8D2/3-323 DE tRNA wybutosine-synthesizing protein 4 #=GS A0A2F0B8D2/3-323 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Cetacea; Mysticeti; Eschrichtiidae; Eschrichtius; Eschrichtius robustus; #=GS E2RSZ5/3-322 AC E2RSZ5 #=GS E2RSZ5/3-322 OS Canis lupus familiaris #=GS E2RSZ5/3-322 DE Leucine carboxyl methyltransferase 2 #=GS E2RSZ5/3-322 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis; Canis lupus; Canis lupus familiaris; #=GS A0A2U3WQI8/3-319 AC A0A2U3WQI8 #=GS A0A2U3WQI8/3-319 OS Odobenus rosmarus divergens #=GS A0A2U3WQI8/3-319 DE tRNA wybutosine-synthesizing protein 4 #=GS A0A2U3WQI8/3-319 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Odobenidae; Odobenus; Odobenus rosmarus; Odobenus rosmarus divergens; #=GS A0A2U3XJX1/3-323 AC A0A2U3XJX1 #=GS A0A2U3XJX1/3-323 OS Leptonychotes weddellii #=GS A0A2U3XJX1/3-323 DE leucine carboxyl methyltransferase 2 #=GS A0A2U3XJX1/3-323 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Phocidae; Leptonychotes; Leptonychotes weddellii; #=GS A0A2Y9LAE1/2-320 AC A0A2Y9LAE1 #=GS A0A2Y9LAE1/2-320 OS Enhydra lutris kenyoni #=GS A0A2Y9LAE1/2-320 DE tRNA wybutosine-synthesizing protein 4 #=GS A0A2Y9LAE1/2-320 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Mustelidae; Lutrinae; Enhydra; Enhydra lutris; Enhydra lutris kenyoni; #=GS G3N0F1/2-323 AC G3N0F1 #=GS G3N0F1/2-323 OS Bos taurus #=GS G3N0F1/2-323 DE Leucine carboxyl methyltransferase 2 #=GS G3N0F1/2-323 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Ruminantia; Pecora; Bovidae; Bovinae; Bos; Bos taurus; #=GS D2GW58/3-323 AC D2GW58 #=GS D2GW58/3-323 OS Ailuropoda melanoleuca #=GS D2GW58/3-323 DE Uncharacterized protein #=GS D2GW58/3-323 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda; Ailuropoda melanoleuca; #=GS A0A3Q7TGR4/3-323 AC A0A3Q7TGR4 #=GS A0A3Q7TGR4/3-323 OS Vulpes vulpes #=GS A0A3Q7TGR4/3-323 DE tRNA wybutosine-synthesizing protein 4 #=GS A0A3Q7TGR4/3-323 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes; Vulpes vulpes; #=GS M3Z802/3-320 AC M3Z802 #=GS M3Z802/3-320 OS Mustela putorius furo #=GS M3Z802/3-320 DE Uncharacterized protein #=GS M3Z802/3-320 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Mustelidae; Mustelinae; Mustela; Mustela putorius; Mustela putorius furo; #=GS Q5XIA3/3-320 AC Q5XIA3 #=GS Q5XIA3/3-320 OS Rattus norvegicus #=GS Q5XIA3/3-320 DE tRNA wybutosine-synthesizing protein 4 #=GS Q5XIA3/3-320 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Rodentia; Myomorpha; Muridae; Murinae; Rattus; Rattus norvegicus; #=GS Q5XIA3/3-320 DR EC; 2.1.1.290; 2.3.1.231; #=GS G7PB67/3-322 AC G7PB67 #=GS G7PB67/3-322 OS Macaca fascicularis #=GS G7PB67/3-322 DE Leucine carboxyl methyltransferase 2 #=GS G7PB67/3-322 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Macaca; Macaca fascicularis; #=GS A0A452SEX8/3-323 AC A0A452SEX8 #=GS A0A452SEX8/3-323 OS Ursus americanus #=GS A0A452SEX8/3-323 DE Leucine carboxyl methyltransferase 2 #=GS A0A452SEX8/3-323 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus; Ursus americanus; #=GS A0A384D0X5/3-323 AC A0A384D0X5 #=GS A0A384D0X5/3-323 OS Ursus maritimus #=GS A0A384D0X5/3-323 DE LOW QUALITY PROTEIN: tRNA wybutosine-synthesizing protein 4 #=GS A0A384D0X5/3-323 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus; Ursus maritimus; #=GS V5IE15/3-309 AC V5IE15 #=GS V5IE15/3-309 OS Ixodes ricinus #=GS V5IE15/3-309 DE Putative carboxymethyl transferase #=GS V5IE15/3-309 DR ORG; Eukaryota; Metazoa; Arthropoda; Chelicerata; Arachnida; Acari; Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes; Ixodes ricinus; #=GS H2NN10/3-323 AC H2NN10 #=GS H2NN10/3-323 OS Pongo abelii #=GS H2NN10/3-323 DE LCMT2 isoform 1 #=GS H2NN10/3-323 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Ponginae; Pongo; Pongo abelii; #=GS A0A2R8ZD65/3-323 AC A0A2R8ZD65 #=GS A0A2R8ZD65/3-323 OS Pan paniscus #=GS A0A2R8ZD65/3-323 DE Uncharacterized protein #=GS A0A2R8ZD65/3-323 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Pan; Pan paniscus; #=GS A0A0D9SEF5/3-323 AC A0A0D9SEF5 #=GS A0A0D9SEF5/3-323 OS Chlorocebus sabaeus #=GS A0A0D9SEF5/3-323 DE Leucine carboxyl methyltransferase 2 #=GS A0A0D9SEF5/3-323 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Chlorocebus; Chlorocebus sabaeus; #=GS A8WHX0/2-322 AC A8WHX0 #=GS A8WHX0/2-322 OS Danio rerio #=GS A8WHX0/2-322 DE Leucine carboxyl methyltransferase 2 #=GS A8WHX0/2-322 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Otomorpha; Ostariophysi; Cypriniphysae; Cypriniformes; Cyprinoidei; Cyprinidae; Danio; Danio rerio; #=GS Q5SQE0/1-310 AC Q5SQE0 #=GS Q5SQE0/1-310 OS Danio rerio #=GS Q5SQE0/1-310 DE Novel protein #=GS Q5SQE0/1-310 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Otomorpha; Ostariophysi; Cypriniphysae; Cypriniformes; Cyprinoidei; Cyprinidae; Danio; Danio rerio; #=GF SQ 37 O60294/3-323 -----PRSRER---RAGAVQNTNDSSALSKRSLAARGYVQDPFAALLVPGAARRAPLIHRGYYVRARAVRHCVRAFLEQIGAPQAALRAQILSLGAGFDSLYF--RLKTAGRL-ARAAVWEVDFPDVARRKAERIGETPELCALTGPFE----RGEPASALCFES------ADYCILGLDLRQL-QRVEEAL-GAAGLDAASPTLLLAEAVLTYLEPESAAALIAWAAQRFPNALFVVYEQMRPQDAFGQFMLQHFRQLNSPLHGLERFPDVEAQRRRFLQAGWTACGAVDMNEFYHCFLPAEERRRVENIEPFDEFEEWHLKCAHYFILAASRGDTLSHTLVF-- Q8BYR1/3-315 -----PRGRQR---RAGTVQSTNDSSSLSKRSLAAHGYVRDPFAALLVPGPVRRTPLIHRGYYVRARAVRHCVRAFLELTSALPSRTRAQILSLGSGSDSLYF--RLKAAGLL-ARAAVWEVDFPDVSRLKAERIEETPELRAQTGPFK----IGDSASSLCFES------ADYRILGADLREL-QRLGEAL-DGAGLDATSPTLLLAEAVLTYLEPSSATALIAWAAQRFPDALFVIYEQMQPGDAFGQIMLQHFQRLHSPLHGLELFPVVKAQRQRFLQAGWTACSALDLNEFYRRLLSAEERQRVETLEPFDEYEEWHLKCSHYFILAASRGD---------- W4XPM5/2-327 --KGKRIHRGTAVQNDIAVQGTNDSSIVSKCSVAMMGYFQDAYLRHFVSKTSRRSPLINRGYFVRARAIDDVLKAFLKKF----GDSKNQIISLGAGFDSTYF--RLQASGSL-ENTAFYEVDFPQLVKRKAALIRNKTELSDLLLNPVYHDDSHQDSFGVCISS------EKYHLVGVDLKQL-DALQSVF-KDIGVDLVVPTLLLSECVITYIDTDSSDALINWAAKTFPNGQFVSYEQVLPDDAFGIIMQKHFKKLNSPLNAIQKYSSKQKHCARFIEQGWQASGAVNMYEYYTQMVTEEERRRVEGIELFDEFEELHLICVHYILVAAFNGRCAECKSS--- W4YET6/2-329 --KGKRIHRGTAVQNDIAVQGTNDSSIVSKCSVAMMGYFQDAYLRHFVSKTSRRSPLINRGYFVRARAIDDILKAFLKKF----GDSKNQIISLGAGFDSTYF--RLQASGSL-DHTAFYEVDFPQLVKRKAALIRKKTELSDLLLNPVYHDEAHEDSFGVCISS------EKYHLVGVDLKQL-DALQSVF-KDIGVDLVVPTLLLSECVITYIDTDSSDALINWAAKTFPNGQFVSYEQVLPDDAFGIVMQKHFKKLNSPLNAIQKYSSKQKHCARFIEQGWLSSGAVNMHEYYTQVISEVERRRVEGIELFDEFEELHLICVHYILVAAFNGRCAEFKASL-F E9G924/1-295 -------MSSS---SDVQVQGSNDWSIASKLSTITAGYYKDSFISCFAQKPVKRSSLIHRGYYVRAKAMHYIFDRFLSQH------PKCQIISFGAGFDTSYY--TLRQQGH--TQCQYVEIDFQDVVSKKWQLIKNHPYCAELAAEK-----------------------DAYQLVAADLRNL-PSLTKLLFEELLMSSSDPTLFISECAITYMDECSSSKLIEWCGTTFPNAVFAVYEQIRPNDGFGRVMQQHFIQLSIPLLSLPVYPDHETQQNRYLHKGWTSCEVYDINEFVHKLVPSDELERMRKLETFDEYEGFNEKCSHYIILTAAKGNCKT------- A7S1F7/1-304 ------------------VQSTNDSSILSKFSMVRAGYFKDEFLKFFVTKDAKRSPLINRGYYIRIKAVSQVLSLFLESSFK-CYSHYLQILSLGAGFDTSFF--RFASEGRL-TNTRFFEVDFPEVVKHKIKFIKQNNLFN----------IPHENELPSGFHS------EDYSLLGCDLKNL-QGLEQKL-LGCGIDTSCPTLLLSEVVLSYLDPISSSAVICWAAKRFDSAVFVSYEQVYPEDPFGVVMINHFNRLGSPLRSITSYPSPQAQVQRYIEKGWTKAQYQDMNSFFNN-LPVEEKQRVEAIEPFDEFEEWHLKCSHYILICGLKGSCEAMAKQM-L A9V7T0/16-172_216-386 TPVLPQQKRRN---HPTAVQGTNDNSILSKCSMAQLGYFDDPFLAEMVQRVTRRSPIINRGYYIRAKAVDHIMSAFLQQH----ADAAPQILSLGAGFDATFF--RLKAAGLLPPGSVYFEVDFPTLIQRKTALIHQSSRLSAHLPEAPIT--SSDALSDLNTPAAQELLYEDYRAVGVDLCKV-KQLRLRL-QAAGLLPDRPTLVLSECVLTYVGPKPAFAVVKWSAEYLSNAILVNYEQIEPDDAFGHFMQGHFTRIGSALKGIGTYRTPRHHNERMIQAGFTTAEAATMGQFYRFLLSDEERLRVDALEPFDEHEEWQLKCLHYIICVAAKGNNLVNF----- F6X2Y1/2-319 ------EGVKS---NSIQVQGTNDSSIVSKLSMATCNYIDDQYLKYFVKKPQRRSALINRGYYLRCKAIEHVLELFLSSN---LECNVKQVVSLGAGFDTRYFWARKYAQKLK-KELVYVEIDFPEVMKRKISL---GTEFGLYQSDF-----SNEQSQNIILRT------ENYAAIGHDLRNMGPQLHSAL-SEVGVNFSQPTLFISEVVLAYLTGSQSSKVISWINHNFSNAFLCIFEQILPQDGFGLVMRRHFEKLGSPLLSICAFPTKESHTLRHKTAGFKVLSSVNLHTFYTNCISQTERTRIENLEMFDEFEGWHQMCLHYIILFSTNSKSSEVAEVCQN B7PPL2/3-309 -----AMTKTA---KHRSVQSTNDSCVISKHSMTCRGYETDDFLHYFVSKPARRSPLINRGYYVRAKCVSRLLLKYCSFL----GKQPCQILSIGAGFDTTFF--RLKSAGVLPTQCRYFEIDLALVVAKKTEVINGSSELSELVGSPVEP-----------------GIWTSYCILNQDLCDL-EGLEASL-SNAKFLFSVPTLLLSECVLSYVDTKHSDKLVAWTARKLQDVMFVVYEQIRPYDAFGIVMLRHFATLGSPLKSLTDYPDPDALKKRYRLLGYDSCECITMREFLDQ-LDPKESLRVRSLEPFDEFEELHEKCNHYVVSLARKGDIFNAF----- A0A2R8PXN4/2-306 -----PVNRKREQGKDAAVQGTNDSSVVSKVSAAAQGYFHDDFLKHFVCKMSRRAPLINRGYYVRWKAIDHCVKQFLHAT---KSCSRRQILSLGAGFDSLFF--RLRAEGAL-GGVTVFEVDFPEVARRKAALINSNACLKDLLPDWETV--LNKQTNAVFISS------GHYNLIGVDVRKE-QEVEASL-SAAGLQWDNPTLILSEVVLTYMETQWSDAVIGWAARLLPQSMFMMYEQIRPDDPFGRVMQSHFLKLNSKIHSLQQYPDTVAQTQRFIQEGWEKCHCMDMNQFYFDLLSEDERERIENLEPFDEFEKQQQKCLN-------------------- E1C573/5-319 ------RPGGR---RSAAVQGTGGSSAVSKCSAAERGYVQDRFVRLLVGRPRRRTALIHRGYYVRARAVDHCVQDFLLKT---QSHPRTQILSLGAGFDSLYF--RLKDMDLL-RHTVIYEVDFPNVACQKATLIKRTEELSALVEDSG----AEGSGVTTAFSG------KDYRLLGVDLSEL-PKLSIAL-EEAGMDNEVPTLFIAEVVLTYMENSRSDALIQWAAEHFSHACFLLYEQMHPEDPFGRVMQQHFRQLNSALRSLSQYPDCEAQQKRFFEKGWTECSVMDMNEFFTCCIPEDEQRRVQALEPFDEYEEWHLKCSHYFVLTASKGMEPSWTP---- A0A2U3VAL4/3-323 -----PRSRER---RAGAVQSTNDSSAVSKTSLAARGYVHDAFAALLVPGTARRAPLIHRGYYVRARAVRHCVRAFLKGTCAVPGAPRAQILSLGAGSDSLYF--RLKTAGRL-TRAAVWEVDFPDVAQRKAQRIRDTPELCALTGPFQ----SGDPGYTLCFES------SDYCILGLDLRQL-QRLDHAL-GTAGLDAAAPTLLLAEAVLTYLEPDDAAALIAWAAQRFSNALFVVYEQMRPRDAFGEFMQQHFRQLNSPLHGLDRFPDAEAQQQRFLQAGWTACRAMDMNEFYRCFLPAEERRRVENLETFDEFEEWHLKCAHYFILAASRGDALSQTLVF-- A0A452DQ16/2-323 ----GSRNRER---RAEAVQSTNDSSALSKSSLAARGYVHDAFAALLVPGTARRAPLIHRGYYVRARAVRHCVRAFVERTCAAPGTPPSQILSLGAGSDSLYF--RLKTAGRL-AGAAVWEVDFPDVAERKAQRIRDTPDLCALTRPFQ----SGDPGSTLCFES------SDYRILGLDLRQL-QQLDQAL-AAAGLDAAAPTLLLAEAVLTYLEPDDAAALISWAAQRFSNAIFVVYEQMRPQDAFGEFMQQHFRHLNSPLHGLDRFPDAEAQQQRFLQAGWTACRAMDLNEFYRCFLPAEERRRMENLEPFDEFEEWHLKCAHYFILAASQGDSLSQTLVF-- A0A3Q7U5X8/3-323 -----PRSRER---RAGAVQSTNDSSALSKSSLAARGYVHDPFAALLVPGTARRAPLIHRGYYVRARAVGHCVRAFLERTCAAPGVPRAQILSLGAGSDSLYF--RLKTAGRL-AGTAVWEVDFPDVARRKAERILDTPELCALTGPFQ----SRDPASALCFES------VDYRLLGLDLRQL-ARLDEAL-AAAGLNAAVPTLLLAEAVLTYLEPNDAAALIAWAARRFPDALFVIYEQMRPHDAFGQVMQQHFQQLNSPLHGLDRFPDVEAQQHRFLQAGWTACCAVDMNEFYRCFLSSEECQRVENLEPFDEFEEWHLKCAHYFILAASRGATLSQTLVF-- F1SI58/3-323 -----PRSRER---RAGAVQSTNDSSALSKSSLAARGYVHDTFAALLVPASVRRAPLIHRGYYVRARAMRHCVCAFLEGTRAALGAPHIQILSLGAGSDSLYF--RLKAAGRL-PGAAVWEVDFPDVARRKADRIRDTPELCALTGPFR----RGDAGSTLCFES------SDYRILGLDLRQV-QRLDQAL-AAAGLDAAAPTLLLAEAVLTYLEPNNAAALIAWAAQCFSDALFVVYEQMRPHDAFGQFMQQHFRQLNSPLHGLDRFPDAEAQQQRFLQAGWTACRALDMNEFYRHFLPAEERRRVENLEPFDEFEEWHLKCSHYFILAASRGDIVSQTVVF-- W5M959/19-337 AVARGAERRKRQVARDVAVQGTNDSSVVSKVSAAMQGYFPDPFLKSFVCRSVRRAPLINRGYYVRWKAVDHCVREFLRGT---AGSTRRQVLSLGAGFDSLYF--RLHSAGAL-EGCVVFELDFPDVSRRKAALVAASPSLMGAVQSPTPP------LQPVCLYS------EQYRLLGADLREL-RGVESAL-MGAGLDPTAPTLLLSEVVLTYMETERSDALIGWAAGLLPHAVFVMYEQLRPHDPFGRVMQEHFRRLSSALHALSEYPDTEAQRRRFLDRGWEHCVCLDMNHFYLGQLGPGERQRVEALEPFDEFEEWHQKCSHYFILTASKGCLTS------- A0A383ZEY6/3-323 -----PRSRER---RAGAVQSTNDSSALSKTSLAARGYVHDTFAALLVPGTARRAPLIHRGYYVRARAVWHCVRAFLKGTCAAPGAPRAQILSLGAGSDSLYF--RLKTAGRV-TRAAVWEVDFPDVAQRKAQRIRDTPELCALTGPFQ----SGDPGYTLCFES------SDYRILGLDLRQL-QRLDHAL-ATAGLDAAAPTLLLAEAVLTYLEPDDAAALIAWAAQRFSNALFVVYEQMRPRDAFGEFMQQHFRQLNSPLHGLDRFPDAEAQQQRFLQAGWTACRAMDMNEFYRCFLTAEERRRVENLETFDEFEEWHLKCAHYFILAASQGDALSQTLVF-- A0A340YIG7/3-323 -----PRSRER---RAGAVQSTNDSSAVSKTSLAARGYVHDAFAALLVPGTARRAPLIHRGYYVRARAVRHCVRAFLKGTCAVPGAPRAQILSLGAGSDSLYF--RLKTAGRL-TRAAVWEVDFPDVAQRKAQRIRDTPELCALTGPFQ----SGDPGYTLCFES------SDYCILGLDLRQL-QRLDHAL-GTAGLDAAAPTLLLAEAVLTYLEPDDAAALIAWAAQRFSNALFVVYEQMRPRDAFGEFMQQHFRQLNSPLHGLDRFPDAEAQQQRFLQAGWTACRAMDMNEFYRCFLPAEERRRVENLETFDEFEEWHLKCAHYFILAASRGDALSQTLVF-- A0A2F0B8D2/3-323 -----PRSRER---RAGAVQSTNDSSALSKTSLAARGYVHDTFAALLVLGTARRAPLIHRGYYVRARAVWHCVRAFLKGTCAAPGTPRAQILSLGAGSDSLYF--RLKTAGRL-TRAAVWEVDFPDVAQRKAQRIRDTPELCALTGPFQ----SGDPGYTLCFES------SDYRILGLDLRQL-QRLDHAL-ATAGLDAAAPTLLLAEAVLTYLEPDDAAALIAWAAQRFSNALFVVYEQMRPRDAFGEFMQQHFRQLNSPLHGLDRFPDAEAQQQRFLQAGWTTCRAMDMNEFYRCFLPAEERRRVENLETFDEFEEWHLKCAHYFILAASRGDALSQTLVF-- E2RSZ5/3-322 -----PRGRER---RSGAVQSTNDSSALSKSSLAAHGYVQDPFAALLVPGTARRAPLIHRGYYVRARAVGHCVRAFLERTCAAPGAPRAQVVSLGAGSDSLYF--RLKTEGRL-TGAAVWEVDFPDVARRKAERIQDTPELCELTGPFQ----SRDPASVLCFEG------ADYRLLGLDLRQL-PRLDQAL-AAAGLDAAAPTLLLAEAVLTYLEPNDAAALIAWAAQRFPDALFVIYEQMRPHDAFGQFMQQHFRQLSSPLHGLDRFPDVEAQQHRFLQAGWTDCRAMDMNEFYRCFLSSEECQRVENLEPFDEFEEWHLKCAHYFILAASTGDTLSQTPV--- A0A2U3WQI8/3-319 -----PRSRER---RAGAVQSTNDSSALSKSSLAAHGYVHDPFAPLLVPGTARRAPLIHRGYYVRARAVGHCVRAFLERTCAAPGAPRAQIVSLGAGSDSLYF--RLKTAGCL-AGAAVWEVDFLDVARRKAERIQDTPELCALTGLFQ----SRDPASALCFES------VDYRLLGLDLRQL-PRLDQAL-AAAGLNAAAPTLLLAEAVLTYLEPSDAAALIAWAAQRFPDALFVIYEQMRPHDAFGQVMQQHFRQLNSPLHGLDCFPDVEAQQHRFLQAGWTACCAVDMNEFYRCFLPSEECQRMENLEPFDEFEEWHLKCAHYFILAASRGDTLSP------ A0A2U3XJX1/3-323 -----PRSRER---RAGAVQSTNDSSALSKSSLAAHGYVHDPFTALLVPGTARRAPLIHRGYYVRARAVGHCVRAFLERTCAAPGAPRAQIVSLGAGSDSLYF--RLKTAGWL-AGAAVWEVDFLDVVRRKAERIQDTPELSALTGPFQ----SRDPASALCFES------VDYRLLGLDLRQL-PRLDQAL-AATGLNAAAPTLLLAEAVLTYLEPSDAAALIAWAAQRFPDALFVIYEQMRPHDAFGQVMQQHFRQINSPLHGLDCFSDVEAQQHRFLQAGWTACCAVDMNEFYRCFLPSEECQRMENLEPFDEFEEWHLKCAHYFILAASRGDTLSQTLVF-- A0A2Y9LAE1/2-320 ----SPRSRER---RAGAVQSTNDSSALSKSSLAAHGYVLDPFAALLVPGTARRAPLIHRGYYVRARAVGHCLRAFLERTCAAPSALRPQILSLGAGSDSLYF--RLKSAGHL-AGAAVWEVDFPDVARRKAERIQDTPELCALTGPFQ----TR--ASALCFES------VDYRLLGVDLRQL-SRLDQAL-AAAGLNAAAPTLLLAEVVLTYLEPKDAAALIAWAAQRFPDAIFVTYEQMRPHDAFGQVMQQHFRQLSSPLHGLDRFPDVEAQKHRFLQAGWTACCAVDMNEFYRCFLPSEECQRVENLEPFDEFEEWHLKCAHYFILAASRGDTLFKTLV--- G3N0F1/2-323 ----GSRNRER---RAEAVQSTNDSSALSKSSLAARGYVHDAFAALLVPGTARRAPLIHRGYYVRARAVRHCVRAFIEQTCAAPGTPRAQILSLGAGSDSLYF--RLKTAGHL-AGAAVWEVDFPDVAERKAQRIRDTPDLCALTGPFQ----SGDHGSTLCFES------SDYRILGLDLRQL-QRLDQAL-AAAGLDAAFPTLLLAEAVLTYLEPDDAAALIAWAAQRFSNAIFVVYEQMRPQDAFGEFMQQHFRHLNSPLHGLDRFPDAEAQQQRFLQAGWTACRAMDLNEFYRCFLPAEERRRMENLEPFDEFEEWHLKCAHYFILAASRGDSLSQTLVF-- D2GW58/3-323 -----PRSRER---RAGAVQSTNDSSALSKSSLAARGYVHDPFAALLVPGTARRAPLIHRGYYVRARAVGHCVRAFLERTCAVPGVTRAQILSLGAGSDSLYF--RLKTAGHL-AGTAVWEVDFPDVARRKAERILDTPELCALTGPFQ----SRDPTSALCFES------VDYRLLGLDLRQL-ARLDEAL-AAAGLNAAAPTLLLAEAVLTYLEPNDAAALIAWAARRFPDALFVIYEQMRPHDAFGQVMQQHFQQLNSPLHGLDRFPDVEAQQNRFLQAGWTACCAVNMNEFYRCFLSSEECQRVENLEPFDEFEEWHLKCAHYFILAASRGATLSQTLVF-- A0A3Q7TGR4/3-323 -----PRGRER---RSGAVQSTNDSSALSKSSLAAHGYVHDPFAALLVPGTARRAPLIHRGYYVRARAVGHCVRAFLERTCAAPGAPRAQVVSLGAGSDSLYF--RLKTEGRL-TGAAVWEVDFPDVARRKAERIQDTPELCGLTGPFQ----SRDPASVLCFES------ADYRLLGLDLRQL-RRLDQAL-AAAGLDAAAPTLLLAEAVLTYLEPNDAAALIAWAAQRFPDALFVIYEQMRPHDAFGQFMQQHFRQLSSPLHGLDRFPDVEAQQHRFLQAGWTDCRAMDMNEFYRCFLSSEECQRVENLEPFDEFEEWHLKCAHYFILAASTGDTLSQTLVF-- M3Z802/3-320 -----PRSRER---RAGAVQSTNDSSALSKSSLAAHGYVLDPFAALLVPGTARRAPLIHRGYYVRARAVGHCVRAFLERTCAAPSALRPQILSLGAGSDSMYF--RLKSAGHL-AGAAVWEVDFPDVARRKAEKIQDTPELCALTGPFQ----TR--ASALCFES------VDYHLLGVDLRQL-SRLDEAL-AAAGLNAAAPTLLLAEAVLTYLEPKDAAALIAWAAQRFSDAIFVTYEQMRPHDAFGQVMQQHFRQLSSPLHGLDRFPDVEAQKHRFLQAGWTACSAVDMNEFYRCFLPSEECQRVENLEPFDEFEEWHLKCAHYFILAASRGHTLFETLV--- Q5XIA3/3-320 -----PRSRQR---RTGTVQSTNDSSSLSKRSLAAQGYVSDAFAPLLVPGIVRRTPLIHRGYYVRARAVRHCVRAFLDLTGAIRSPTRAQILSLGSGSDSLYF--RLKAAGLL-TRTAVWEVDFPDVSRLKAKRIEETPELCAQTGPFK----IGDSASTLCFES------SDYRILGADLREL-QRLGEAL-DSAGLDATSPTLILAEAVLTYLEPSRAAALIAWVAQRFPNALFVIYEQMKPGDAFGQIMLQHFRRLNSPLHGLELFPDVEAQRQRFLQAGWTTCSALDLNEFYRRLIPADERRRVETLEPFDEFEEWHLKCSHYFILAASRGDILSET----- G7PB67/3-322 -----PRNRER---RAGAVQSTNDSSALSKRSLAARGYVQDPFAALLVPGAARRAPLIHRGYYIRARAVRHCVRAFLEQTGALHAARRAQILSLGAGFDSLYF--RLKTAGRL-ARAAVWEVDFPNVARRKAERIGETPELCALTGPFQ----RGEPASALCFES------ADYCILGLDLRQL-QRVDEAL-GAAGLDAASPTLLLAEAVLTYLETESAAALIAWAAQRFPNALFVVYEQMRPQDAFGQFMLQHFRQLNSPLHGLERFPDVEAQRRRFLQAGWTACGAVDMNEFYRCFLPAEERRRVENIEPFDEFEEWHLKCAHYFILAASRGDILSHTLV--- A0A452SEX8/3-323 -----PRSRER---RAGAVQSTNDSSALSKSSLAARGYVHDPFAALLVPGIARRAPLIHRGYYVRARAVGHCVRAFLERTCAAPGVPRAQILSLGAGSDSLYF--RLKTAGRL-AGTAVWEVDFPDVARRKAERILDTPELCALTGPFQ----SRDPASALCFES------VDYRLLGLDLRQL-ARLDEAL-AAAGLNAAVPTLLLAEAVLTYLEPNDAAALIAWAARRFPDALFVIYEQMRPHDAFGQVMQQHFQQLNSPLHGLDRFPDVEAQQHRFLQAGWTACCAVDMNEFYRCFLSSEECQRVENLEPFDEFEEWHLKCAHYFILAASRGATLSQTLVF-- A0A384D0X5/3-323 -----PRSRER---RAGAVQSTNDSSALSKSSLAARGYVHDPFAALLVPGTARRAPLIHRGYYVRARAVGHCVRAFLERTCAAPGVPRAQILSLGAGSDSLYF--RLKTAGRL-AGTAVWEVDFPDVARRKAERILDTPELCALTGPFQ----SRDPASALCFES------VDYRLLGLDLRQL-ARLDEAL-AAAGLNAAVPTLLLAEAVLTYLEPNDAAALIAWAARRFPDALFVIYEQMRPHDAFGQVMQQHFQQLNSPLHGLDRFPDVEAQQHRFLQAGWTACCAVDMNEFYRCFLSSEECQRVENLEPFDEFEEWHLKCAHYFILAASRGATLSQTLVF-- V5IE15/3-309 -----AMTKTA---KHRSVQSTNDSCVISKHSMTCRGYETDDFLHYFVSKPARRSPLINRGYYVRAKCVSRLLLKYCSFL----GKQSCQIVSIGAGFDTTFF--RLKSAGVLPTQCRYFEIDLALVVAKKTEVINGSSELSKLVGSPVEP-----------------GIWTDYCILNQDLCDL-AGLEASL-SNAKFLFSVPTLLLSECVLSYVETKHSDKLVAWTARKFQDVMFVVYEQIRPYDAFGIVMLRHFATLGSPLISLTDYPDPDALKERYRSLGYDSCECITMREFFDQ-LDPKESLRVRLLEPFDEFEELHEKCNHYVVSLARKGDVFHAF----- H2NN10/3-323 -----PRSRER---RAGAVQNTNDSSALSKRSLAARGYVQDPFAALLVPGAARRAPLIHRGYYVRARAVSHCVRAFLEQTGAPQAALRAQILSLGAGFDSLYF--RLKTAGRL-ARAAVWEVDFPDVARRKAERIGETPELCALTGPFQ----RGEPASALCFES------ADYCILGLDLRQL-QRVEEAL-GAAGLDAASPTLLLAEAVLTYLEPESAAALIAWAAQRFPNALFVVYEQMRPQDAFGQFMLQHFRQLNSPLHGLERFPDVEAQRRRFLQAGWTACRAVDMNEFYHCFLPAEERRRVENIEPFDEFEEWHLKCAHYFILAASRGDTLSHTLVF-- A0A2R8ZD65/3-323 -----PRSRER---RAGAVQNTNDSSALSKRSLAARGYVQDPFAALLVPGAARRAPLIHRGYYVRARAVRHCVRAFLEQIGAPQAALRAQILSLGAGFDSLYF--RLKTAGRL-ARAAVWEVDFPEVARRKAERIGETPELCALTGPFQ----RGEPASALCFES------ADYCILGLDLRQL-QRVEEAL-GAAGLDAASPTLLLAEAVLTYLEPESAAALIAWAAQRFPNALFVVYEQMRPQDAFGQCMLQHFRQLNSPLHGLERFPDVEAQRRRFLQAGWTACGAVDMNEFYHCFLPAEERRRVENIEPFDEFEEWHLKCAHYFILAASRGDTLSHTLVF-- A0A0D9SEF5/3-323 -----PRSRER---RAGAVQSTNDSSALSKRSLAARGYVQDPFAALLVPGAARRAPLIHRGYYIRARAVRHCVRAFLEQTGAPHAARRAQILSLGAGFDSLYF--RLKTAGRL-ARAAVWEVDFPDVARRKAERIGETPELCALTGPFR----RGEPASALCFES------ADYCILGLDLRQL-QRVDEAL-GAAGLDAASPTLLLAEAVLTYLETESAAALIAWAAQRFPNALFVVYEQMRPQDAFGQFMLQHFRQLNSPLHGLERFPDVEAQRRRFLQAGWTACGAVDMNEFYRCFLPAEERRRVENIEPFDEFEEWHLKCAHYFILAASRGDTLSHTLVF-- A8WHX0/2-322 -----PVNRKREQGKDAAVQGTNDSSVVSKVSAAAQGYFHDDFLKHFVCKMSRRAPLINRGYYVRWKAVDHCVKQFLHAT---KSCSRRQILSLGAGFDSLFF--RLRAEGAL-GGVTVFEVDFPEVARRKAALINSNACLKDLLPDWETV--LNKQTNAVFISS------GHYNLIGADVRKE-QEVEASL-SAAGLQWDNPTLILSEVVLTYMETQWSDAVIGWAARLLPQSMFVMYEQIHPDDPFGRVMQSHFLKLNSKIHSLQQYPDNVAQTQRFIQEGWEKCHCLDMNQFYFDLLPEDERQRIENLEPFDEFEEWHQKCSHYFILTASKGSVTRQAL---- Q5SQE0/1-310 ----------------PQVQGTNDSSVVSKVSAAAQGYFHDDFLKHFVCKMSRRAPLINRGYYVRWKAIDHCVKQFLHAT---KSCSRRQILSLGAGFDSLFF--RLRAEGAL-GGVTVFEVDFPEVARRKAALINSNACLKDLLPDWETV--LNKQTNAVFISS------GHYNLIGVDVRKE-QEVEASL-SAAGLQWDNPTLILSEVVLTYMETQWSDAVIGWAARLLPQSMFMMYEQIRPDDPFGRVMQSHFLKLNSKIHSLQQYPDTVAQTQRFIQEGWEKCHCMDMNQFYFDLLSEDERERIENLEPFDEFEEWHQKCSHYFILTASKGSVTRQAL---- #=GC scorecons 0000033354400053359958887856993957548944948544684545896789699987967774656448743512124345398697989596578008765583704445549798757556964473455574464443300002232333444350000003594567498656044753580346764343999676948779665336477849685475564874899659496994595599458586855743776356644975549754635467668743375459549775796999797675794885654745743332322100 #=GC scorecons_70 __________________**_*****__**_*_*__**__*_*___**____**_***_******_***_*_*__**____________********_**_**__**___*_*_______*****_*__***__*_____*________________________________*__**_***_*___*___*___***____*****_*_****_*_____***_***__*__*_**_****_*_****__*__**__*_***__*__***__**__**___**__*___******___*___*__***_*********_*_**_**_*__*__*___________ #=GC scorecons_80 __________________**_*****__**_*_*__**__*_*____*____**_***_******_***______**____________**_*****_*__**__**___*_*_______*****_*___*___*_____*________________________________*___*_**__________*____*_____***_*_*_****________**_*_*__*____*__***__*_*_**__*__**__*_*_*__*__**_______**___*________*__**_______*__*___**_******_*_**_**____*__*___________ #=GC scorecons_90 __________________**_***_*__**_*____**__*_*____*____**__**_****_*__________*_____________**_*_***_*___*__*______________*_**______*__________________________________________*_____*___________*__________***___*_*__*_________*_*_________*__***__*_*_**__*__**__*_*________________*____*___________*________*__*____*_***_*_____*_**___________________ //