# STOCKHOLM 1.0 #=GF ID 3.40.1190.10/FF/000011 #=GF DE Folylpolyglutamate synthase/dihydrofolate synthase #=GF AC 3.40.1190.10/FF/000011 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 95.007 #=GS B0R3B1/1-292 AC B0R3B1 #=GS B0R3B1/1-292 OS Halobacterium salinarum R1 #=GS B0R3B1/1-292 DE Folylpolyglutamate synthase / 7,8-dihydropteroate reductase / dihydropteroate synthase #=GS B0R3B1/1-292 DR ORG; Archaea; Euryarchaeota; Halobacteria; Halobacteriales; Halobacteriaceae; Halobacterium; Halobacterium salinarum; #=GS B0R3B1/1-292 DR EC; 2.5.1.15; 6.3.2.17; #=GS Q74AI6/1-284 AC Q74AI6 #=GS Q74AI6/1-284 OS Geobacter sulfurreducens PCA #=GS Q74AI6/1-284 DE Folylpolyglutamate synthetase #=GS Q74AI6/1-284 DR ORG; Bacteria; Proteobacteria; delta/epsilon subdivisions; Deltaproteobacteria; Desulfuromonadales; Geobacteraceae; Geobacter; Geobacter sulfurreducens; #=GS Q74AI6/1-284 DR GO; GO:0004326; GO:0006760; GO:0008841; #=GS Q9RXH3/28-282 AC Q9RXH3 #=GS Q9RXH3/28-282 OS Deinococcus radiodurans R1 #=GS Q9RXH3/28-282 DE Folyl-polyglutamate synthetase #=GS Q9RXH3/28-282 DR ORG; Bacteria; Deinococcus-Thermus; Deinococci; Deinococcales; Deinococcaceae; Deinococcus; Deinococcus radiodurans; #=GS Q7NL38/6-238 AC Q7NL38 #=GS Q7NL38/6-238 OS Gloeobacter violaceus PCC 7421 #=GS Q7NL38/6-238 DE Folyl-polyglutamate synthetase #=GS Q7NL38/6-238 DR ORG; Bacteria; Cyanobacteria; Gloeobacteria; Gloeobacterales; Gloeobacteraceae; Gloeobacter; Gloeobacter violaceus; #=GS Q7UQM1/90-380 AC Q7UQM1 #=GS Q7UQM1/90-380 OS Rhodopirellula baltica SH 1 #=GS Q7UQM1/90-380 DE Folylpolyglutamate synthase/dihydrofolate synthase #=GS Q7UQM1/90-380 DR ORG; Bacteria; Planctomycetes; Planctomycetia; Planctomycetales; Planctomycetaceae; Rhodopirellula; Rhodopirellula baltica; #=GS O67833/2-280 AC O67833 #=GS O67833/2-280 OS Aquifex aeolicus VF5 #=GS O67833/2-280 DE Folylpolyglutamate synthetase #=GS O67833/2-280 DR ORG; Bacteria; Aquificae; Aquificae; Aquificales; Aquificaceae; Aquifex; Aquifex aeolicus; #=GS A9WDT0/1-298 AC A9WDT0 #=GS A9WDT0/1-298 OS Chloroflexus aurantiacus J-10-fl #=GS A9WDT0/1-298 DE FolC bifunctional protein #=GS A9WDT0/1-298 DR ORG; Bacteria; Chloroflexi; Chloroflexia; Chloroflexales; Chloroflexineae; Chloroflexaceae; Chloroflexus; Chloroflexus aurantiacus; #=GS A0A0H2UNA3/1-293 AC A0A0H2UNA3 #=GS A0A0H2UNA3/1-293 OS Streptococcus pneumoniae TIGR4 #=GS A0A0H2UNA3/1-293 DE Dihydrofolate synthetase #=GS A0A0H2UNA3/1-293 DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; #=GS A0A0H2UN62/2-285 AC A0A0H2UN62 #=GS A0A0H2UN62/2-285 OS Streptococcus pneumoniae TIGR4 #=GS A0A0H2UN62/2-285 DE Putative dihydrofolate synthetase #=GS A0A0H2UN62/2-285 DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; #=GS Q89WE2/2-298 AC Q89WE2 #=GS Q89WE2/2-298 OS Bradyrhizobium diazoefficiens USDA 110 #=GS Q89WE2/2-298 DE Folylpolyglutamate synthase #=GS Q89WE2/2-298 DR ORG; Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Bradyrhizobiaceae; Bradyrhizobium; Bradyrhizobium diazoefficiens; #=GS A2G107/2-273 AC A2G107 #=GS A2G107/2-273 OS Trichomonas vaginalis #=GS A2G107/2-273 DE FolC bifunctional protein #=GS A2G107/2-273 DR ORG; Eukaryota; Trichomonadida; Trichomonadidae; Trichomonas; Trichomonas vaginalis; #=GS A0A3M1WC33/1-298 AC A0A3M1WC33 #=GS A0A3M1WC33/1-298 OS Chloroflexi bacterium #=GS A0A3M1WC33/1-298 DE Bifunctional folylpolyglutamate synthase/dihydrofolate synthase #=GS A0A3M1WC33/1-298 DR ORG; Bacteria; Chloroflexi; Chloroflexi bacterium; #=GS M2AYD5/66-350 AC M2AYD5 #=GS M2AYD5/66-350 OS Rhodopirellula europaea 6C #=GS M2AYD5/66-350 DE Folylpolyglutamate synthase/dihydrofolate synthase #=GS M2AYD5/66-350 DR ORG; Bacteria; Planctomycetes; Planctomycetia; Planctomycetales; Planctomycetaceae; Rhodopirellula; Rhodopirellula europaea; #=GS F9MIC5/2-285 AC F9MIC5 #=GS F9MIC5/2-285 OS Streptococcus mitis SK569 #=GS F9MIC5/2-285 DE Bifunctional protein FolC #=GS F9MIC5/2-285 DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus mitis; #=GS A0A0X8CCK4/2-298 AC A0A0X8CCK4 #=GS A0A0X8CCK4/2-298 OS Bradyrhizobium sp. CCGE-LA001 #=GS A0A0X8CCK4/2-298 DE Bifunctional folylpolyglutamate synthase/dihydrofolate synthase #=GS A0A0X8CCK4/2-298 DR ORG; Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Bradyrhizobiaceae; Bradyrhizobium; Bradyrhizobium sp. CCGE-LA001; #=GS A0A150ZH09/2-298 AC A0A150ZH09 #=GS A0A150ZH09/2-298 OS Bradyrhizobium sp. DOA1 #=GS A0A150ZH09/2-298 DE Folylpolyglutamate synthase #=GS A0A150ZH09/2-298 DR ORG; Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Bradyrhizobiaceae; Bradyrhizobium; Bradyrhizobium sp. DOA1; #=GS I0FXS6/2-298 AC I0FXS6 #=GS I0FXS6/2-298 OS Bradyrhizobium sp. S23321 #=GS I0FXS6/2-298 DE Folylpolyglutamate synthase #=GS I0FXS6/2-298 DR ORG; Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Bradyrhizobiaceae; Bradyrhizobium; Bradyrhizobium sp. S23321; #=GS A0A0R3DB08/2-298 AC A0A0R3DB08 #=GS A0A0R3DB08/2-298 OS Bradyrhizobium manausense #=GS A0A0R3DB08/2-298 DE Bifunctional folylpolyglutamate synthase/dihydrofolate synthase #=GS A0A0R3DB08/2-298 DR ORG; Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Bradyrhizobiaceae; Bradyrhizobium; Bradyrhizobium manausense; #=GS Q9HS44/1-292 AC Q9HS44 #=GS Q9HS44/1-292 OS Halobacterium salinarum NRC-1 #=GS Q9HS44/1-292 DE Probable bifunctional folylpolyglutamate synthase/dihydropteroate synthase #=GS Q9HS44/1-292 DR ORG; Archaea; Euryarchaeota; Halobacteria; Halobacteriales; Halobacteriaceae; Halobacterium; Halobacterium salinarum; #=GS Q9HS44/1-292 DR EC; 2.5.1.15; 6.3.2.17; #=GS A0A0H2ZQI4/1-293 AC A0A0H2ZQI4 #=GS A0A0H2ZQI4/1-293 OS Streptococcus pneumoniae D39 #=GS A0A0H2ZQI4/1-293 DE Folylpolyglutamate synthase #=GS A0A0H2ZQI4/1-293 DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; #=GS Q8DR92/1-293 AC Q8DR92 #=GS Q8DR92/1-293 OS Streptococcus pneumoniae R6 #=GS Q8DR92/1-293 DE Dihydrofolate synthetase #=GS Q8DR92/1-293 DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; #=GS Q54614/1-293 AC Q54614 #=GS Q54614/1-293 OS Streptococcus pneumoniae #=GS Q54614/1-293 DE Dihydrofolate synthetase #=GS Q54614/1-293 DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; #=GS A5M4R5/1-293 AC A5M4R5 #=GS A5M4R5/1-293 OS Streptococcus pneumoniae SP14-BS69 #=GS A5M4R5/1-293 DE Folylpolyglutamate synthase #=GS A5M4R5/1-293 DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; #=GS A0A0T8UIN3/1-293 AC A0A0T8UIN3 #=GS A0A0T8UIN3/1-293 OS Streptococcus pneumoniae #=GS A0A0T8UIN3/1-293 DE Dihydrofolate synthetase #=GS A0A0T8UIN3/1-293 DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; #=GS A0A0T7JHT8/1-294 AC A0A0T7JHT8 #=GS A0A0T7JHT8/1-294 OS Streptococcus pneumoniae #=GS A0A0T7JHT8/1-294 DE Dihydrofolate synthetase #=GS A0A0T7JHT8/1-294 DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; #=GS A0A0T8UJG9/1-293 AC A0A0T8UJG9 #=GS A0A0T8UJG9/1-293 OS Streptococcus pneumoniae #=GS A0A0T8UJG9/1-293 DE Folylpolyglutamate synthase #=GS A0A0T8UJG9/1-293 DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; #=GS A0A0H2ZQ04/1-287 AC A0A0H2ZQ04 #=GS A0A0H2ZQ04/1-287 OS Streptococcus pneumoniae D39 #=GS A0A0H2ZQ04/1-287 DE Folylpolyglutamate synthase #=GS A0A0H2ZQ04/1-287 DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; #=GS Q8DRE0/1-287 AC Q8DRE0 #=GS Q8DRE0/1-287 OS Streptococcus pneumoniae R6 #=GS Q8DRE0/1-287 DE Dihydrofolate:folylpolyglutamate synthetase #=GS Q8DRE0/1-287 DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; #=GS A0A0U0MLH8/2-285 AC A0A0U0MLH8 #=GS A0A0U0MLH8/2-285 OS Streptococcus pneumoniae #=GS A0A0U0MLH8/2-285 DE Dihydrofolate synthetase #=GS A0A0U0MLH8/2-285 DR ORG; Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pneumoniae; #=GS A0A2A6N6K3/2-298 AC A0A2A6N6K3 #=GS A0A2A6N6K3/2-298 OS Bradyrhizobium diazoefficiens #=GS A0A2A6N6K3/2-298 DE Bifunctional folylpolyglutamate synthase/dihydrofolate synthase #=GS A0A2A6N6K3/2-298 DR ORG; Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Bradyrhizobiaceae; Bradyrhizobium; Bradyrhizobium diazoefficiens; #=GS A0A0E4BPP1/3-298 AC A0A0E4BPP1 #=GS A0A0E4BPP1/3-298 OS Bradyrhizobium diazoefficiens #=GS A0A0E4BPP1/3-298 DE Folylpolyglutamate synthase #=GS A0A0E4BPP1/3-298 DR ORG; Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Bradyrhizobiaceae; Bradyrhizobium; Bradyrhizobium diazoefficiens; #=GF SQ 31 B0R3B1/1-292 --------MRYDEAANFLLDL----RRYGPKPG-----TESTADLLASLGDPHQDGP-------DYVQIAGSNGKGSTARFTESILRAAGLDVGLYTSPHFDDVRERVTV----NGRRMSKAALTTFIETITPYVT-ERAADGAAPTYFEVVTAMALWQFSRADVDVAVLEVGIGGRLDATSVV-DPSASAVTSVTLEHTDVLGETIPEIARDKAHVAPAGDTPLVTATT-DDALAAVRDHAGAVR-TVGDTAGRDVTATYE---GRT-----NHTEAAVSITGD-DW---SVATEIP-LLGDHQAENAGVAAALARQTAG------VDDDAIARGLRSAHWP Q74AI6/1-284 --------MTYGEILAHIYGL----RRFGIRPG-----LERIATLLQRLGNPQERL--------RVVHVAGTNGKGSTAAFLASILAEGGYRAGLFTSPHLTRFTERFRI----NGTEIAEEAAARVAGQV-------LASAPEGTTFFEVVTAMALLHFVEEGVDAAILEAGMGGGADATSAA-TGILTVIAPVALDHCEWLGETIPAIAREKAGLIRAG-RPVVLSRQPAEARDVFIERGRILG-APLVCFGADFSAAWD--ESSL-----AYDGLSRQLAGL----------RPG-IGGRYQLANAATALAAAEILADNGFR--LDSPALRAGIDAARWP Q9RXH3/28-282 ----DY---------DWLYAQ----TRAGRERG-----PGPARALLDRLGAPDRKF--------QTIRVVGTNGKGSTCAMLEAGLLAAGVRAGRFTSPHLHAYEERIRV----GGENLDPARTAQFIDWAKQ--------NAPGEAFFDLTLALACQAFAEAGVDWAVMEAGVGGVSDATQALGNVRAVALTNADLDHTATLGPTIRDIASDKAGVAQAG-VPLLTTAT-GEALDVVREVAAELG-APLFTPQTHPDLFAV-------------------------------PHAPS-LSGPHQRTNAALALATLRVLGFERGA----EAALNAS------- Q7NL38/6-238 -------------------------------------LVAGTRALLDRVGAPDRTM--------ECVLVGGTSGKGSVATGLAAHCERAGVRVGLHTSPYLQVATEKIRL----DGQYIGGAEFAELVEWIWPHLEAWRDPAHLRRRYGAVSLVLAAEAMRRHGAQVGVFEVGCGGRFDPVNAL-AARAVAITTVGLDHVALLGPTLADIAWQKAGLIKSA-APVVTAAR-GLPLQIIQREAASYG-APVRCTPAD---------------------------------------------------NAALAGALFEVCRGTPAPR-LPPQAVRLPGR----- Q7UQM1/90-380 ----------------------------GQSPP-----SSENQSSVVELARPDSIVQPSKSTGVQIVHLAGTKGKGSAATMVAALLHSAGYRVGLYTSPHLVNLEERFRV----DGEIATPEEMIGLIDSMRPIVEAMTAAPIGGPSFFELTTAMAIEHFHRRQCDIWVLETGLGGRLDSTNVF-QSHATAITSIGLDHQHVLGDTAELIAAEKAGIFKRD-TPAINGVPAGPVRDVIVRIANQIG-APLMHLGDEIQITPN--TESQ-----KCWGSSFQISGLGDWMPGDTVVDLK-LEGAHQIRNAAIALALVDALPDV-TRKLRPEQCIHQCLSSL--- O67833/2-280 ------------GILWELYKE----KDFDVKPT-----LERIKKACEYIGNPQKNY--------PSILVGGTNGKGSTCAFTERILREHGFKTGWFVSPHLISENERWRI----NGKPIQEEVLKDYVKDLKKVFEKF------SLTYFEAATLIAVKYFEDQGINVAVFEVGMGGRWDATKVS-EAGVRGITNVERDHTRWLGDTVEKIAEEKLGLYEEG-KPLIL----GSARYPLYTRALELGLKNLKVAGIDYEYWGKVERERTVLE--KYESENFSLEGA----------QLS-LWGKWQIDNASLAITLSSEFTK------LSPEKVNQALKNTVWE A9WDT0/1-298 MQI-----TTYQEALDYIYSFIDPTRQGSPDPAIAARSLARLRALLDIAGNPHQQL--------AAVVVAGTKGKGSTCALIEAMARAAGLRVGLWTSPHLSSYRERIQI----DREPISQATLIQLVRDVQPIVDAFDTATYGRPSTFDIGFVMAMRHFVAAHVDLAVVEVGLGGRFDAAATI-TPLIAVISSISYDHMAILGPTLHDIAYNKAGIMRPG-RPAITVPQHPEAAAVFAAEAQTVG-APLWLAAEHTVEPWL-----ASGQPLTYP------APP----------QPGRLRGGFQRENARLAMGTALLLRDQGVP--IDDQAIRRGLAEA-W- A0A0H2UNA3/1-293 --------MKEIENNQWIANY----RTDQPHFG-----LERMVELLALRGNPHLKL--------KVLHIGGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISI----NGESISEARLEALMADYQSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVC-QPILTGITTIGLDHVALLGDTLEVIAEQKAGIIKQG-MPLVTGRIAPEALAVIDRIAEGKD-APRLAYGTDYQVRHQ--ESVVTGEVFDYTSAVRQ-GRF----------QTS-LLGLYQIENAGMAIALLDTFCQEDGRELASNDFLGQALEE---- A0A0H2UN62/2-285 -----------FEVEEWLHSR----IGLNFRSG-----LGRMQQAVDLLGNPEQSY--------PIIHVTGTNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICI----NGQPIADADFIRLTDQVKE-MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVV-TGEFAVITSIGLDHQETLGDSLEAIAEQKAGIFKAG-KKAVIAKLPPEARLACQKKAESLA-VNLYQAGQDFLMLNG-----------DFSSSLLNLSQL----------NIG-LEGVYQQENAALALQTFLLFMRE-RKEAVDEQAVRKALEQTHWA Q89WE2/2-298 NASPDSAKPPLDELIGRLSAL----HQKRIDLG-----LERMHRLLDRLGHPERKLP-------PVIHIAGTNGKGSTLAYLRATLEAADLRVHAYTSPYLVRINECFRLGRLGGGVLVGDDELRAALEEV------ERVNAGEPATVFELKTAAAFHLFAQNPADAVLLEVGLGGRLDSTNVVDTPAATVITPVSMDHTDFLGDTLTSIAGEKAAIIKRG-VPVVCAEQSGEAMAVIEAQAKRMR-APLFAANESWHVNVE--HGRL-----VYSDDRGLMDLA----------APR-LFGRHQFDNAGLAIATLRAIST--FK--VNQAAFEAGIVGAEWP A2G107/2-273 --------NGYESLVKNLINSSKSSLHFNQDQK-----LQYIGQYLHHFYNDHLEI--------PSIVVAGTKGKGSTCAVIESILRHSGLKTGLFTSPHLETPRERIKI----NGVSISGDEYISSYHNI---TSKLSTSGFKQPPFFGLHTLMSIDVFEKHNIDIAVIECGVGGRFDWTKIY-SPLTSVITHLEYDHLETLGKTAQSIAWHKAGIFAKD-IPALTAPQNKPFMDELVRCAQLEG-TDLKVVCPFWNE------------------------------------KMG-LHGPTAKENSSLGIEAAKTVAKKIGI--SHLKGIAKGVENAKI- A0A3M1WC33/1-298 MQI-----TTYQEALDYIYSFIDPTRQGSPDPAIAARSLARLRALLDIAGNPHQQL--------AAVVVAGTKGKGSTCALIEAMARAAGLRVGLWTSPHLSSYRERIQI----DREPISQATLIQLVRDVQPIVDAFDTATYGRPSTFDIGFVMAMRHFVAAHVDLAVVEVGLGGRFDAAATI-TPLIAVISSISYDHMAILGPTLHDIAYNKAGIMRPG-RPAITVPQHPEAAAVFAAEAQTVG-APLWLAAEHTVEPWL-----ASGQPLTYP------APP----------QPGRLRGGFQRENARLAMGTALLLRDQGVP--IDDQAIRRGLAEA-W- M2AYD5/66-350 ---------------------------------------SETNSAADESAKPDSIIQPGESTGVQIVHLAGTKGKGSAATMVAALLHQAGYRVGLYTSPHLVHLEERFRV----DGENATPEEMIGLIDSMRPIVEAMAAAPIGGPSFFELTTAMAIEHFHRRQCDVWVLETGLGGRLDSTNVF-QSHATAITSIGLDHQHVLGETKELIAAEKAGIFKRD-TPAINGVPSGPVRDVIVRIADQIS-APLTHLGDDIQITPD--TASQ-----KCWGSSFQISGLGDWLPADTVVDLK-LEGAHQVRNAAIALALVDALPDV-TRKLRPEQRIHQCLSSL--- F9MIC5/2-285 -----------FEVEEWLHSR----IGLNFRSG-----LSRMQQAVDLLGNPEKSY--------PIIHVTGTNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICI----NGEPIADADFIRLAEQVKE-MEKTLVQTHDQLSFFELLTLIAFLYFREQEVDLVLLEVGIGGLLDTTNVV-TGEIAVITSIGLDHQETLGDSLEAIAEQKAGIFKSG-KKAVIAKLAPEARLVCQKKAESLA-VDLYHAGQDFSMLNR-----------DFSSSLLNISQL----------KIG-LEGAYQQENATLALQAFLLFMRE-GRESVDEQAVREALKQTHWA A0A0X8CCK4/2-298 NASPDSAKTPLGEVIGRLSVL----HQKRIDLG-----LERMHRLLERLGHPERKLP-------PVIHIAGTNGKGSTLAYLRAMLEASGQRVHAYTSPYLVRINECFRLGRAGGGVLVGDDELRAALEEV------ERVNAGEAATVFELKTAAAFHLFAQNPADVVLLEVGLGGRLDSTNVVDTPAACVITPVSMDHMEFLGDTLASIAGEKAAIIKRG-VPVICAEQEPDAMAVIEAQAKRMR-APLFAANESWHVNVE--RGRL-----VYSDDRGLMDLP----------APR-LFGRHQFANAGLAIATLRALPH--LK--VNHVAFEAGIVGAEWP A0A150ZH09/2-298 NASPDSAKTPLGEVIGRLSVL----HQKRIDLG-----LERMHRLLERLGHPERKLP-------PVIHIAGTNGKGSTLAYLRAMLEASGQRVHAYTSPYLVRINECFRLGRAGGGVLVGDDELRAALEEV------ERVNAGEAATVFELKTAAAFHLFAQNPADVVLLEVGLGGRLDSTNVVDTPAACVITPVSMDHMEFLGDTLASIAGEKAAIIKRG-VPVICAEQEPDAMAVIEAQAKRMR-APLFAANESWHVNVE--RGRL-----VYSDDRGLMDLP----------APR-LFGRHQFANAGLAIATLRALPH--LK--VNHVAFEAGIVGAEWP I0FXS6/2-298 NASADNAKPPLGELIGRLSAL----HQKRIDLG-----LERMHRLLERLGHPERKLP-------PVIHIAGTNGKGSTLAYLRATLEAAGLRVHAYTSPYLVRINECFRIGRVGGGVLVGDDELRAALEEV------ERVNAGEAATVFELKTAAAFHLFAQNPADVVLLEVGLGGRLDSTNVIDTPAACVITPISMDHMDFLGDTLTSIAGEKAAIIKRG-VPVICAEQTPEAMAVIEAEAKRMR-APLFAANESWHVNVE--HGRL-----VYSDERGLMDLA----------APR-LFGRHQFDNAGLAIATLRAIPV--FT--VNHAAFEAGIVGAEWP A0A0R3DB08/2-298 NASPDSTKASLDALIGRLSAL----HQKRIDLG-----LERMHRLLERLDHPERKLP-------PVIHVAGTNGKGSTVAYLRATLEAASLRVHAYTSPYLVRINECFRLGRLGGGVLVTDDELLAALEQV------ERVNAGEPATVFELKTAAAFLLFAQNPADAVLLEVGLGGRLDSTNVVDTPAACVITPVSMDHMDFLGSTLASIAAEKAAIIKRG-VPVVCAEQTGEAMAVIEAQARQMR-APLFAANESWHVNVE--HGRL-----VYSDERGLMDLA----------APR-LFGRHQFDNAGLAIATLRAIST--FK--VNQAAFEAGIVAAEWP Q9HS44/1-292 --------MRYDEAANFLLDL----RRYGPKPG-----TESTADLLASLGDPHQDGP-------DYVQIAGSNGKGSTARFTESILRAAGLDVGLYTSPHFDDVRERVTV----NGRRMSKAALTTFIETITPYVT-ERAADGAAPTYFEVVTAMALWQFSRADVDVAVLEVGIGGRLDATSVV-DPSASAVTSVTLEHTDVLGETIPEIARDKAHVAPAGDTPLVTATT-DDALAAVRDHAGAVR-TVGDTAGRDVTATYE---GRT-----NHTEAAVSITGD-DW---SVATEIP-LLGDHQAENAGVAAALARQTAG------VDDDAIARGLRSAHWP A0A0H2ZQI4/1-293 --------MKEIENNQWIANY----RTDQPHFG-----LERMVELLALRGNPHLKL--------KVLHIGGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISI----NGESISEARLEALMADYQSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLFDSTNVC-QPILTGITTIGLDHVALLGDTLEAIAEQKAGIIKQG-MPLVTGRIAPEALAVIDRIAEGKD-APRLAYGTDYQVRHQ--ESVVTGEVFDYTSAVRQ-GRF----------QTS-LLGLYQIENAGMAIALLDTFCQEDGRELASNDFLGQALEE---- Q8DR92/1-293 --------MKEIENNQWIANY----RTDQPHFG-----LERMVELLALRGNPHLKL--------KVLHIGGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISI----NGESISEARLEALMADYQSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLFDSTNVC-QPILTGITTIGLDHVALLGDTLEAIAEQKAGIIKQG-MPLVTGRIAPEALAVIDRIAEGKD-APRLAYGTDYQVRHQ--ESVVTGEVFDYTSAVRQ-GRF----------QTS-LLGLYQIENAGMAIALLDTFCQEDGRELASNDFLGQALEE---- Q54614/1-293 --------MKEIENNQWIANY----RTDQPHFG-----LERMVELLALRGNPHLKL--------KVLHIGGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISI----NGESISEARLEALMADYQSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLFDSTNVC-QPILTGITTIGLDHVALLGDTLEAIAEQKAGIIKQG-MPLVTGRIAPEALAVIDRIAEGKD-APRLAYGTDYQVRHQ--ESVVTGEVFDYTSAVRQ-GRF----------QTS-LLGLYQIENAGMAIALLDTFCQEDGRELASNDFLGQALEE---- A5M4R5/1-293 --------MKEIENNQWIANY----RTDQPHFG-----LERMVELLALRGNPHLKL--------KVLHIGGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISI----NGESISEARLEALMADYQSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVC-QPILTGITTIGLDHVALLGDTLEAIAEQKAGIIKQG-MPLVTGRIAPEALTVIDRIAEGKD-APRLAYGTDYQVRHQ--ESVVTGEVFDYTSAVRQ-GRF----------QTS-LLGLYQIENAGMAIALLDTFCQEDGRELASNDFLGQALEE---- A0A0T8UIN3/1-293 --------MKEIENNQWIANY----RTDQPHFG-----LERMVELLALRGNPHLKL--------KVLHIGGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISI----NGESISEARLEALMADYQSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVC-QPILTGITTIGLDHVALLGDTLEAIAEQKAGIIKQG-MPLVTGRIAPEALTVIDRIAEGKD-APRLAYGTDYQVRHQ--ESVVTGEVFDYTSAIRQ-GRF----------QTS-LLGLYQIENAGMAIALLDTFCQEDGRELASNDFLGQALEE---- A0A0T7JHT8/1-294 --------MKEFENNQWIAHY----RTDQPHFG-----LERMVELLALRGNPHLKL--------KVIHVGGTNGKGSTIAFLKNMLEKMGLRVGVFSSPYLIHYTDQISI----NGESIPEARLEALMGDYQSLLEGEAAANLQGTTEFEIITAIAYDYFASEQVDVAIMEVGMGGLLDSTNVC-QPILTGITTIGLDHVALLGDTLEAIAEQKAGIIKQG-IPLVTGHIAPEALAVIDCIAEGKD-APRLAYGANYHVSHQ--ENVVTGEVFDYTSSLRQ-GRF----------QTG-LLGLHQIENAGMAIALLDTFCKEDGRELVSNDLLGQALEET--- A0A0T8UJG9/1-293 --------MKEIENNQWIANY----RTDQPHFG-----LERMVELLALRGNPHLKL--------KVLHIGGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISI----NGESISEARLEALMADYQSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVC-QPILTGITTIGLDHVALLGDTLEAIAEQKAGIIKQG-MPLVTGRIAPEALTVIDRIAEGKD-APRLAYGTDYQVRHQ--ESVVTGEVFDYTSAIRQ-GRF----------QTS-LLGLYQIENAGMAIALLDTFCQEDGRELASNDFLGQALEE---- A0A0H2ZQ04/1-287 --------MCMFEVKEWLHSR----IGLNFRSG-----LGRMQQAVDLLGNPEQSY--------PIIHVTGTNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICI----NGQPIADADFIRLADQVKE-MEKTLLQTPDQLSFFELLTLVAFLYFRGQEVDLVLLEVGIGGLLDTTNVV-TGELAVITSIGLDHQETLGDSLEAIAEQKAGIFKAG-KKAVIAKLPPEARLVCQKKAESLA-VNLYQAGQDFSVLNG-----------DFSSSLLNLSQL----------NIG-LEGVYQQENAALALQTFLLFMGE-GKEAVDEQAVRKALEQTHWA Q8DRE0/1-287 --------MCMFEVKEWLHSR----IGLNFRSG-----LGRMQQAVDLLGNPEQSY--------PIIHVTGTNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICI----NGQPIADADFIRLADQVKE-MEKTLLQTPDQLSFFELLTLVAFLYFRGQEVDLVLLEVGIGGLLDTTNVV-TGELAVITSIGLDHQETLGDSLEAIAEQKAGIFKAG-KKAVIAKLPPEARLVCQKKAESLA-VNLYQAGQDFSVLNG-----------DFSSSLLNLSQL----------NIG-LEGVYQQENAALALQTFLLFMGE-GKEAVDEQAVRKALEQTHWA A0A0U0MLH8/2-285 -----------FEVEEWLHSR----IGLNFRSG-----LGRMQQAVDLLGNPEQSY--------PIIHVTGTNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICI----NGQPIADADFIRLTDQVKE-MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVV-TGELAVITSIGLDHQETLGDSLEAIAEQKAGIFKAG-KKAVIAKLPPEARLVCQKKAESLA-VNLYQAGQDFLMLNG-----------DFSSSLLNLSQL----------NIG-LEGVYQQENAALALQTFLLFMGE-GKEAVDEQAVRKALEQTHWA A0A2A6N6K3/2-298 NASPDSAKPPLDELIGRLSAL----HQKRIDLG-----LERMHRLLDRLGHPERKLP-------PVIHIAGTNGKGSTLAYLRATLEAADLRVHAYTSPYLVRINECFRLGRLGGGVLVGDDELRAALEEV------ERVNAGEPATVFELKTAAAFHLFAQNPADAVLLEVGLGGRLDSTNVVDTPAATVITPVSMDHTDFLGDTLTSIAGEKAAIIKRG-VPVVCAEQSGEAMAVIEAQAKRMR-APLFAANESWHVNVE--HGRL-----VYSDDRGLMDLA----------APR-LFGRHQFDNAGLAIATLRAIST--FK--VNQAAFEAGIVGAEWP A0A0E4BPP1/3-298 -ASPDSAKPPLGELIGRLSAL----HQKRIDLG-----LERMHRLLDRLGHPERKLP-------PVIHIAGTNGKGSTLAYLRATLEAADLRVHAYTSPYLVRINECFRLGRLGGGVLVGDDELRAALEEV------ERVNAGEPATVFELKTAAAFHLFAQNPADAVLLEVGLGGRLDSTNVVDTPAATVITPVSMDHTDFLGDTLTSIAGEKAAIIKRG-VPVVCAEQSGEAMAVIEAQAKRMR-APLFAANESWHVNVE--HGRL-----VYSDDRGLMDLA----------APR-LFGRHQFDNAGLAIATLRAIST--FK--VNQAAFEAGIVGAEWP #=GC scorecons 0000000021115223352320000332333350000065553356434758534400000000446565986999974755444644474675466997743347554600005843644545345444422123133444234453875375484348434458555696959945957664045344587465589343995764499359867464703756453324574465343843340655344535334223001212000003533222213220000000000344072825735985685554344332023114444454455333121 #=GC scorecons_70 _____________________________________________*___*_*______________*_*_********_*_____*___*_**__******____*___*_____*__*_____________________________**__*__*___*_____*____***_**__*_*_*________**_*__**___**_*___**__****_*_*__*_*_______*__*____*_____*___________________________________________________*_*__*__**__*_______________________________ #=GC scorecons_80 _________________________________________________*_*__________________**_*****___________*__*____**______*_________*________________________________**_____*___*_____*____*_*_**__*_*__________**____**___**_*___**__**_*___*____________*_______*_________________________________________________________*_*__*__**__*_______________________________ #=GC scorecons_90 ___________________________________________________*__________________**_****____________________**________________*________________________________*______*___*_____*____*_*_**__*____________*_____**___**_____**__**__________________________*___________________________________________________________*_____**__*_______________________________ //