# STOCKHOLM 1.0 #=GF ID 3.30.930.10/FF/000121 #=GF DE Histidine--tRNA ligase #=GF AC 3.30.930.10/FF/000121 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 88.266 #=GS Q55D12/54-398 AC Q55D12 #=GS Q55D12/54-398 OS Dictyostelium discoideum #=GS Q55D12/54-398 DE Probable histidine--tRNA ligase, mitochondrial #=GS Q55D12/54-398 DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium discoideum; #=GS Q55D12/54-398 DR GO; GO:0004821; GO:0006427; #=GS Q55D12/54-398 DR EC; 6.1.1.21; #=GS Q8ZWZ1/6-329 AC Q8ZWZ1 #=GS Q8ZWZ1/6-329 OS Pyrobaculum aerophilum str. IM2 #=GS Q8ZWZ1/6-329 DE Histidine--tRNA ligase #=GS Q8ZWZ1/6-329 DR ORG; Archaea; Crenarchaeota; Thermoprotei; Thermoproteales; Thermoproteaceae; Pyrobaculum; Pyrobaculum aerophilum; #=GS Q8ZWZ1/6-329 DR EC; 6.1.1.21; #=GS Q980L3/2-332 AC Q980L3 #=GS Q980L3/2-332 OS Saccharolobus solfataricus P2 #=GS Q980L3/2-332 DE Histidine--tRNA ligase #=GS Q980L3/2-332 DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Saccharolobus; Saccharolobus solfataricus; #=GS Q980L3/2-332 DR EC; 6.1.1.21; #=GS Q9RUN5/1-333 AC Q9RUN5 #=GS Q9RUN5/1-333 OS Deinococcus radiodurans R1 #=GS Q9RUN5/1-333 DE Histidine--tRNA ligase #=GS Q9RUN5/1-333 DR ORG; Bacteria; Deinococcus-Thermus; Deinococci; Deinococcales; Deinococcaceae; Deinococcus; Deinococcus radiodurans; #=GS Q9RUN5/1-333 DR EC; 6.1.1.21; #=GS A9WK42/3-203_262-390 AC A9WK42 #=GS A9WK42/3-203_262-390 OS Chloroflexus aurantiacus J-10-fl #=GS A9WK42/3-203_262-390 DE Histidine--tRNA ligase #=GS A9WK42/3-203_262-390 DR ORG; Bacteria; Chloroflexi; Chloroflexia; Chloroflexales; Chloroflexineae; Chloroflexaceae; Chloroflexus; Chloroflexus aurantiacus; #=GS P47281/3-316 AC P47281 #=GS P47281/3-316 OS Mycoplasma genitalium G37 #=GS P47281/3-316 DE Histidine--tRNA ligase #=GS P47281/3-316 DR ORG; Bacteria; Tenericutes; Mollicutes; Mycoplasmatales; Mycoplasmataceae; Mycoplasma; Mycoplasma genitalium; #=GS P47281/3-316 DR EC; 6.1.1.21; #=GS F0ZXL8/1-321 AC F0ZXL8 #=GS F0ZXL8/1-321 OS Dictyostelium purpureum #=GS F0ZXL8/1-321 DE Uncharacterized protein #=GS F0ZXL8/1-321 DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium purpureum; #=GS C4KIQ9/2-331 AC C4KIQ9 #=GS C4KIQ9/2-331 OS Sulfolobus islandicus M.16.4 #=GS C4KIQ9/2-331 DE Histidine--tRNA ligase #=GS C4KIQ9/2-331 DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Sulfolobus; Sulfolobus islandicus; #=GS C4KIQ9/2-331 DR EC; 6.1.1.21; #=GS D0KRX2/2-332 AC D0KRX2 #=GS D0KRX2/2-332 OS Saccharolobus solfataricus 98/2 #=GS D0KRX2/2-332 DE Histidine--tRNA ligase #=GS D0KRX2/2-332 DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Saccharolobus; Saccharolobus solfataricus; #=GS D0KRX2/2-332 DR EC; 6.1.1.21; #=GS A0A0E3MBV6/2-332 AC A0A0E3MBV6 #=GS A0A0E3MBV6/2-332 OS Saccharolobus solfataricus #=GS A0A0E3MBV6/2-332 DE Histidine--tRNA ligase #=GS A0A0E3MBV6/2-332 DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Saccharolobus; Saccharolobus solfataricus; #=GS A0A0E3MBV6/2-332 DR EC; 6.1.1.21; #=GS C3MRE4/2-331 AC C3MRE4 #=GS C3MRE4/2-331 OS Sulfolobus islandicus L.S.2.15 #=GS C3MRE4/2-331 DE Histidine--tRNA ligase #=GS C3MRE4/2-331 DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Sulfolobus; Sulfolobus islandicus; #=GS C3MRE4/2-331 DR EC; 6.1.1.21; #=GS C3MY40/2-331 AC C3MY40 #=GS C3MY40/2-331 OS Sulfolobus islandicus M.14.25 #=GS C3MY40/2-331 DE Histidine--tRNA ligase #=GS C3MY40/2-331 DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Sulfolobus; Sulfolobus islandicus; #=GS C3MY40/2-331 DR EC; 6.1.1.21; #=GS C3N7K1/2-331 AC C3N7K1 #=GS C3N7K1/2-331 OS Sulfolobus islandicus Y.G.57.14 #=GS C3N7K1/2-331 DE Histidine--tRNA ligase #=GS C3N7K1/2-331 DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Sulfolobus; Sulfolobus islandicus; #=GS C3N7K1/2-331 DR EC; 6.1.1.21; #=GS C3NFX3/2-331 AC C3NFX3 #=GS C3NFX3/2-331 OS Sulfolobus islandicus Y.N.15.51 #=GS C3NFX3/2-331 DE Histidine--tRNA ligase #=GS C3NFX3/2-331 DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Sulfolobus; Sulfolobus islandicus; #=GS C3NFX3/2-331 DR EC; 6.1.1.21; #=GS C3MZH9/2-331 AC C3MZH9 #=GS C3MZH9/2-331 OS Sulfolobus islandicus M.16.27 #=GS C3MZH9/2-331 DE Histidine--tRNA ligase #=GS C3MZH9/2-331 DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Sulfolobus; Sulfolobus islandicus; #=GS C3MZH9/2-331 DR EC; 6.1.1.21; #=GF SQ 15 Q55D12/54-398 --INLQN-IKGTYDLFPN---------EQRIHKFIFDVGRGVAERYGFKEISTPIIEPFELFNRSVGESSDIVMKEM---FKFKDYSNESSSPPSMICLRPEGTAGVIRAIINQSSTNHLTPAQRYYYQGPMFRYERPQRGRQRQFHQLGVELIGDQHPRSDVEIIDMAMNFIERLGINKSDTLLKINSLGDTDSI-KVYNETLKRFYNDNVNKLSPISI---------KRLERGNSL----RILDSKERQDIELNKL---------APS--IQDSLSIQCKDRFNNVLKG---LDCLGISYE---IDKSL-VRGLDYYRHTIFEIQIIDNNQNNKGQRQQQQQQQGLAILGGGRYDGLANQLGYKYKEILPSIGWASGIERMVLFLDQSKI-- Q8ZWZ1/6-329 --DHLRRPVRGMRDWLPP---------QYYALRHMEEVLCKVAESFGYRRVETPVVEHFEVLAKKAGQ--DVI-NEI---YYFKDKAGRD------LGLRFDMTVPVARVLSYN---LELPRPVRWYYFTKVFRYDEPQHGRYREFYQFGVELVGSSSPRADAEVIQLLIASLEAAGASN--FYVRINDRRAVDKLLEHLG---VAPYRDIIYKALDKKL----------KLPREDVI----KIMTGGGVSKEIAEEIYNTATEITIQEAVELLYKLDKALGASYEKIVKY---LEA-SVPMERLKFDMSI-VRGLDYYTGIVFEAFVGEYK---------------LAVGGGGRYDDLLELYSGVK---TPALGFAIGVERLMEAVGIQNV-- Q980L3/2-332 --VKFET-VRGMKDYIGI---------DAEKIRYLESTFRDLAKKYGYSEIITPVVEEFKLFELKGGE--ELR-QTM---YVFKDKADRE------ISLRPEITPSVARAYIQN--LQSSPKPIRLFYFGTVYRYDEPQYGRYREFRQAGIEMIGDSSILADVEVLDLLYNFYDKLNLSKD-ITIKINNIGIFRKIMDKYN--IEDNLQEHVLHLIDKNKVDEALVILEKNIKNKDIMDFLNMILTKKEAKLEDIESL---------AE---LEEVSKLDIKNEFEYLLRLSRILSSLNVKFK---VDLGF-VRGLAYYTGLIFEVLHPSVQ---------------FSIAGGGRYDKLIELYGGLP---SPAIGFAIGVERTLLVIKDLKVEE Q9RUN5/1-333 --MAIQR-PKGTNDLLPSGSPKTEAFQRAAAHEWLIAQAREVLERAGAQRIDTPMFEEAELVKRGVGGSTDIVRKEMFTVYYFGDHGG--------YVLRPEGTASIVRAYLENG-LKQLPAPLKLWTSGPMFRAERHQKGRYRQFTQVDYEVLGSADALVDAEAIALMVAVVQKLGLRG--VRVKLGSIGDPEDR-ERYNAYLRDLFSPHLGRLSDDSK---------DRLER-NPM----RILDSKSASDQELLAE---------LSVRPMLDFLGEGAAADFRQVQAY---LSDWGVPFD---LDPSI-VRGLDYYRRTAWELHYEGIGAK-------------SALGGGGRYDGLSEQLGGGS---VPGIGWAFGVERLLLALEQEGIEI A9WK42/3-203_262-390 GAVSIDL-VRGMRDVHPA---------EFAHGRYIQRILEQTMAGYGYQMIDTPVIEHRELYLRKLGE--DLV-GKV---YEF-SFGGRD------LALRPEWTASVLRAYVAS--MQDQPLPLRLSYAGPVFRYERPQRYTYRQFTQVGGEIIGGLPPRADAEVIALACAGLQAVGVTE--YTVRIGHIGLARELLSRFA--LPERTRGLLVWSLERLRAEGIAPVR-ERADE-QPL------VEAALEQLARLAAISG-----PPEHAIPMLADLPGSESAAFRELQAILNLLAAYHIPAERVVIDGALGRRGLHYYTGLIFEIYDREGN----------------QLCGGGRYDDLVGALGGRQ--ATPAVGFAYGLERVTAAATTG---- P47281/3-316 F---LQK-PRGVKDWFGD---------ELVYFNWIVKKIRSLAFNWGFSEVKTPLFENAQLFQRSNAN-ADIVQKEL---YQFFDKSQRE------LALRPEATTPIVRLACENKLMQEANFPLKLFCIGSMYRYERPQNNRFREHWQFSCEVFGFSNLFIFLDTLLFANSLLEALGITG--YVLKINNLANFETL-SKWNKALKDYLTPYKLELTELSQ---------KRLEK-NPL----RILDDKIDQKKSFVKN---------APK--ITDFLDASAKQDSELLKTQ---LKKHNISFE---WTDNL-VRGLDYYTGFVFEYV--KNQ---------------DTILAGGVYDNLVEELSSNP---TPALGFACGIERLINCLEIDKK-- F0ZXL8/1-321 ----LKS-IKGTYDYFPN---------EKRVYSFVNQIGKSVSELYGYEEISTPIIEPFELFNRSVGEYSDIVMKEM---FTFKDLSGQA------ICLRPEGTAGVIRAIINEGSTTSTSPTQKYYYSGPMFRYERPQKGRQRQFEQFGAELIGDSHPRSDVEIIDMAYHFIEKLGIPSDQFHLKINSLGDKNSI-KTYSDALTEFYQGKIDKLSPDSI---------KRLQRGNAL----RILDSKDKGDIEINKD---------APL--LQNYLSDSCKQRFKSVLEG---LDNLGIKYQ---IDNGL-VRGLDYYRHTIFEIIILKDN---------------LAILGGGRYDGLANNIGYKHNEILPSIGWASGIDRILIYINQDI--- C4KIQ9/2-331 --TKFET-VRGMKDYIGI---------DAEKIRYLESTFRDLAIKYGYSEIITPVVEEFKLFALKGGE--ELR-ETM---YVFKDKADRE------LSLRPEITPSVARAYIQN--LQSSPKPIRLFYFGTVYRYDEPQYGRYREFRQAGIEMIGDSSILADLEVLDLLYNFYDKLNLSND-ITIKINNIGIFRKIMDKYN--IEDNLQEHILHLIDKNKINEALDILEKNLKNKDIIDFFNKILTKKDTKLEDIESL---------AE---LEEVSRLDIKSEFLYLFRLSRILSNLNIKFK---IDLGF-VRGLAYYTGLIFEVLHPSVQ---------------FSIAGGGRYDKLIELYGGLP---SPAIGFAIGVERTLLVIKDLKVE- D0KRX2/2-332 --VKFET-VRGMKDYIGI---------DAEKIRYLESTFRDLAKKYGYSEIITPVVEEFKLFELKGGE--ELR-QTM---YVFKDKADRE------ISLRPEITPSVARAYIQN--LQSSPKPIRLFYFGTVYRYDEPQYGRYREFRQAGIEMIGDSSILADVEVLDLLYNFYDKLNLSKD-ITIKINNIGIFRKIMDKYN--IEDNLQEHVLHLIDKNKVDEALVILEKNIKNKDIMDFLNMILTKKEAKLEDIESL---------AE---LEEVSKLDIKNEFEYLLRLSRILSSLNVKFK---VDLGF-VRGLAYYTGLIFEVLHPSVQ---------------FSIAGGGRYDKLIELYGGLP---SPAIGFAIGVERTLLVIKDLKVEE A0A0E3MBV6/2-332 --VKFET-VRGMKDYIGI---------DAEKIRYLESTFRDLAKKYGYSEIITPVVEEFKLFELKGGE--ELR-QTM---YVFKDKADRE------ISLRPEITPSVARAYIQN--LQSSPKPIRLFYFGTVYRYDEPQYGRYREFRQAGIEMIGDSSILADVEVLDLLYNFYDKLNLSKD-ITIKINNIGIFRKIMDKYN--IEDNLQEHVLHLIDKNKVDEALVILEKNIKNKDIMDFLNMILTKKEAKLEDIESL---------AE---LEEVSKLDIKNEFEYLLRLSRILSSLNVKFK---VDLGF-VRGLAYYTGLIFEVLHPSVQ---------------FSIAGGGRYDKLIELYGGLP---SPAIGFAIGVERTLLVIKDLKVEE C3MRE4/2-331 --TKFET-VRGMKDYIGI---------DAEKIRYLESTFRDLAIKYGYSEIITPVVEEFKLFALKGGE--ELR-ETM---YVFKDKADRE------LSLRPEITPSVARAYIQN--LQSSPKPIRLFYFGTVYRYDEPQYGRYREFRQAGIEMIGDSSILADLEVLDLLYNFYDKLNLSND-ITIKINNIGIFRKIMDKYN--IEDNLQEHILHLIDKNKINEALDILEKNLKNKDIIDFFNKILTKKDTKLEDIESL---------AE---LEEVSRLDIKSEFLYLFRLSRILSNLNIKFK---IDLGF-VRGLAYYTGLIFEVLHPSVQ---------------FSIAGGGRYDKLIELYGGLP---SPAIGFAIGVERTLLVIKDLKVE- C3MY40/2-331 --TKFET-VRGMKDYIGI---------DAEKIRYLESTFRDLAIKYGYSEIITPVVEEFKLFALKGGE--ELR-ETM---YVFKDKADRE------LSLRPEITPSVARAYIQN--LQSSPKPIRLFYFGTVYRYDEPQYGRYREFRQAGIEMIGDSSILADLEVLDLLYNFYDKLNLSND-ITIKINNIGIFRKIMDKYN--IEDNLQEHILHLIDKNKINEALDILEKNLKNKDIIDFFNKILTKKDTKLEDIESL---------AE---LEEVSRLDIKSEFLYLFRLSRILSNLNIKFK---IDLGF-VRGLAYYTGLIFEVLHPSVQ---------------FSIAGGGRYDKLIELYGGLP---SPAIGFAIGVERTLLVIKDLKVE- C3N7K1/2-331 --TKFET-VRGMKDYIGI---------DAEKIRYLESTFRDLAIKYGYSEIITPVVEEFKLFALKGGE--ELR-ETM---YVFKDKADRE------LSLRPEITPSVARAYIQN--LQSSPKPIRLFYFGTVYRYDEPQYGRYREFRQAGIEMIGDSSILADLEVLDLLYNFYDKLNLSND-ITIKINNIGIFRKIMDKYN--IEDNLQEHILHLIDKNKINEALDILEKNLKNKDIIDFFNKILTKKDTKLEDIESL---------AE---LEEVSRLDIKSEFLYLFRLSRILSDLNIKFK---IDLGF-VRGLAYYTGLIFEVLHPSVQ---------------FSIAGGGRYDKLIELYGGLP---SPAIGFAIGVERTLLVIKDLKVE- C3NFX3/2-331 --TKFET-VRGMKDYIGI---------DAEKIRYLESTFRDLAIKYGYSEIITPVVEEFKLFALKGGE--ELR-ETM---YVFKDKADRE------LSLRPEITPSVARAYIQN--LQSSPKPIRLFYFGTVYRYDEPQYGRYREFRQAGIEMIGDSSILADLEVLDLLYNFYDKLNLSND-ITIKINNIGIFRKIMDKYN--IEDNLQEHILHLIDKNKINEALDILEKNLKNKDIIDFFYKILTKKDTKLEDIESL---------AE---LEEVSRLDIKSEFLYLFRLSRILSDLNIKFK---IDLGF-VRGLAYYTGLIFEVLHPSVQ---------------FSIAGGGRYDKLIELYGGLP---SPAIGFAIGVERTLLVIKDLKVE- C3MZH9/2-331 --TKFET-VRGMKDYIGI---------DAEKIRYLESIFRDLAIKYGYSEIITPVVEEFKLFALKGGE--ELR-ETM---YVFKDKADRE------LSLRPEITPSVARAYIQN--LQSSPKPIRLFYFGTVYRYDEPQYGRYREFRQAGIEMIGDSSILADLEVLDLLYNFYDKLNLSND-IIIKINNIGIFRKIMDKYN--IEDNLQEHILHLIDKNKINEALDILEKNLKNKDIIDFFNKILTKKDTKLEDIESL---------AE---LEEVSRLDIKSEFLYLFRLSRILSNLNIKFK---IDLGF-VRGLAYYTGLIFEVLHPSVQ---------------FSIAGGGRYDKLIELYGGLP---SPAIGFAIGVERTLLVIKDLKVE- #=GC scorecons 0022553057954944530000000005333355533436455345964573996594558634537600764044600073947454540000005499783955759645460045436374755637467977579467696739463956945444574866465344455655442043578655633445244660053534444534645444111110111556452545111147754633434454440000000005400063435334353473363431119434474550005735507999499654679433243400000000000000034637997994946347534000496696949689454454334320 #=GC scorecons_70 _________**__*________________________________**__*_***_*___**____*___*_____*___*_*_*_____________****_*__*_**____________*_*__*_*_*****_**_**_***_*_*_*_**______*_*_*_*_______*_________***__*_______________________*________________*___________**__*____________________________________*__*______*____*_______*____****_**___***________________________*_******_*_*__*_______****_*_****____________ #=GC scorecons_80 _________**__*________________________________*___*_**__*___*_____*_____________*_*_*_____________****_*__*_*_______________*____*__***__**__*_*_*_*___*__*______*_*_____________________**________________________________________________________**_________________________________________________*____*_______*____****_**____**__________________________******_*____________*__*_*_*_**____________ #=GC scorecons_90 __________*__*________________________________*_____**__*_________________________*_______________**_*_*____*________________________*____*____*___*___*__*________*__________________________________________________________________________________________________________________________________*__________________***_**_____*___________________________**_**_*____________*__*_*_*_**____________ //