The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Elongation factor G

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 15 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
37 A5PKR8 (/ISS) A7RR04 (/ISS) B0W010 (/ISS) B0WGM1 (/ISS) B3M011 (/ISS) B3MK91 (/ISS) B3N6A5 (/ISS) B3P8M3 (/ISS) B4GNT0 (/ISS) B4HEQ8 (/ISS)
(27 more)
Translation elongation factor activity GO:0003746
Functions in chain elongation during polypeptide synthesis at the ribosome.
30 A5PKR8 (/ISS) A7RR04 (/ISS) B0WGM1 (/ISS) B3MK91 (/ISS) B3N6A5 (/ISS) B4HY41 (/ISS) B4HY41 (/ISS) B4HY41 (/ISS) B4JQM7 (/ISS) B4KKD5 (/ISS)
(20 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
21 P28371 (/IPI) P28371 (/IPI) Q2G0N1 (/IPI) Q2G0N1 (/IPI) Q2G0N1 (/IPI) Q2G0N1 (/IPI) Q2G0N1 (/IPI) Q2G0N1 (/IPI) Q2G0N1 (/IPI) Q2G0N1 (/IPI)
(11 more)
Translation elongation factor activity GO:0003746
Functions in chain elongation during polypeptide synthesis at the ribosome.
4 P13551 (/IDA) P13551 (/IDA) Q96RP9 (/IDA) Q96RP9 (/IDA)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
4 Q9C641 (/IDA) Q9C641 (/IDA) Q9SI75 (/IDA) Q9SI75 (/IDA)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
2 P13551 (/IMP) P13551 (/IMP)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
2 Q96RP9 (/HDA) Q96RP9 (/HDA)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
2 Q96RP9 (/IDA) Q96RP9 (/IDA)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
2 P13551 (/IDA) P13551 (/IDA)
GDP binding GO:0019003
Interacting selectively and non-covalently with GDP, guanosine 5'-diphosphate.
2 P13551 (/IMP) P13551 (/IMP)
Ribosome binding GO:0043022
Interacting selectively and non-covalently with any part of a ribosome.
2 P13551 (/IDA) P13551 (/IDA)
GTPase activity, coupled GO:0061745
Catalysis of the reaction: GTP + H2O = GDP + phosphate; this reaction directly drives some other reaction.
2 P13551 (/IDA) P13551 (/IDA)
Translation elongation factor activity GO:0003746
Functions in chain elongation during polypeptide synthesis at the ribosome.
1 Q8K0D5 (/ISO)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
1 Q8K0D5 (/ISO)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
1 E1BEJ3 (/TAS)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrial translational elongation GO:0070125
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion.
25 A5PKR8 (/ISS) A7RR04 (/ISS) B0WGM1 (/ISS) B3MK91 (/ISS) B3N6A5 (/ISS) B4HY41 (/ISS) B4HY41 (/ISS) B4HY41 (/ISS) B4JQM7 (/ISS) B4KKD5 (/ISS)
(15 more)
Mitochondrial translation GO:0032543
The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.
13 B0W010 (/ISS) B3M011 (/ISS) B3P8M3 (/ISS) B4GNT0 (/ISS) B4HEQ8 (/ISS) B4JSI3 (/ISS) B4M416 (/ISS) B4NAU8 (/ISS) B4PMC6 (/ISS) Q29BD5 (/ISS)
(3 more)
Ribosome disassembly GO:0032790
The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits.
12 B0W010 (/ISS) B3M011 (/ISS) B3P8M3 (/ISS) B4GNT0 (/ISS) B4HEQ8 (/ISS) B4JSI3 (/ISS) B4M416 (/ISS) B4NAU8 (/ISS) B4PMC6 (/ISS) Q29BD5 (/ISS)
(2 more)
Translational elongation GO:0006414
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.
5 Q9KPM5 (/ISS) Q9KUZ7 (/ISS) Q9KUZ7 (/ISS) Q9KUZ7 (/ISS) Q9KUZ7 (/ISS)
Oxidative phosphorylation GO:0006119
The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.
3 Q38BA0 (/IMP) Q38BA0 (/IMP) Q38BA0 (/IMP)
Translational elongation GO:0006414
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.
2 P13551 (/IDA) P13551 (/IDA)
Chloroplast organization GO:0009658
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chloroplast.
2 Q9SI75 (/IMP) Q9SI75 (/IMP)
Post-embryonic development GO:0009791
The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development.
2 Q9SI75 (/IMP) Q9SI75 (/IMP)
Seed germination GO:0009845
The physiological and developmental changes that occur in a seed commencing with water uptake (imbibition) and terminating with the elongation of the embryonic axis.
2 Q9SI75 (/IMP) Q9SI75 (/IMP)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
2 F4IW10 (/IEP) F4IW10 (/IEP)
Mitochondrial translational elongation GO:0070125
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion.
2 Q96RP9 (/IDA) Q96RP9 (/IDA)
Mitochondrial translational elongation GO:0070125
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion.
2 Q96RP9 (/TAS) Q96RP9 (/TAS)
Mitochondrial translational elongation GO:0070125
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion.
1 Q8K0D5 (/ISO)

There are 16 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
172 O30913 (/IDA) P0A6M8 (/IDA) P0A6M8 (/IDA) P0A6M8 (/IDA) P0A6M8 (/IDA) P0A6M8 (/IDA) P0A6M8 (/IDA) P0A6M8 (/IDA) P0A6M8 (/IDA) P0A6M8 (/IDA)
(162 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
171 P0A6M8 (/HDA) P0A6M8 (/HDA) P0A6M8 (/HDA) P0A6M8 (/HDA) P0A6M8 (/HDA) P0A6M8 (/HDA) P0A6M8 (/HDA) P0A6M8 (/HDA) P0A6M8 (/HDA) P0A6M8 (/HDA)
(161 more)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
12 P9WNM7 (/HDA) P9WNM7 (/HDA) P9WNM7 (/HDA) P9WNM7 (/HDA) P9WNM7 (/HDA) P9WNM7 (/HDA) P9WNM7 (/HDA) P9WNM7 (/HDA) P9WNM7 (/HDA) P9WNM7 (/HDA)
(2 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
12 P9WNM7 (/HDA) P9WNM7 (/HDA) P9WNM7 (/HDA) P9WNM7 (/HDA) P9WNM7 (/HDA) P9WNM7 (/HDA) P9WNM7 (/HDA) P9WNM7 (/HDA) P9WNM7 (/HDA) P9WNM7 (/HDA)
(2 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
10 F4IW10 (/IDA) F4IW10 (/IDA) Q38BA0 (/IDA) Q38BA0 (/IDA) Q38BA0 (/IDA) Q9C641 (/IDA) Q9C641 (/IDA) Q9SI75 (/IDA) Q9SI75 (/IDA) Q9VM33 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 Q38BA0 (/IDA) Q38BA0 (/IDA) Q38BA0 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
3 Q38BA0 (/RCA) Q38BA0 (/RCA) Q38BA0 (/RCA)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
3 E1BEJ3 (/TAS) Q96RP9 (/TAS) Q96RP9 (/TAS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q55E94 (/ISS) Q9VCX4 (/ISS)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
2 Q9SI75 (/IDA) Q9SI75 (/IDA)
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
2 Q9SI75 (/IDA) Q9SI75 (/IDA)
Chloroplast envelope GO:0009941
The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
2 Q9SI75 (/IDA) Q9SI75 (/IDA)
Apoplast GO:0048046
The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it.
2 Q9SI75 (/IDA) Q9SI75 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9VM33 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q4Q219 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q8K0D5 (/HDA)